Tissue distribution of bovine spongiform encephalopathy infectivity in Romney sheep up to the onset of clinical disease after oral challenge

Sixty Romney sheep of three prion protein genotypes were dosed orally at six months of age with an inoculum prepared from the brains of cattle clinically affected with BSE, and 15 sheep were left undosed as controls. They were randomly assigned within genotype to groups and were sequentially euthana...

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Veröffentlicht in:	Veterinary record 2005-02, Vol.156 (7), p.197-202
Hauptverfasser:	Bellworthy, S. J., Hawkins, S. A. C., Green, R. B., Blamire, I., Dexter, G., Dexter, I., Lockey, R., Ryder, S., Berthelin-Baker, C., Simmons, M. M., Jeffrey, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Encephalopathy, Bovine Spongiform - pathology Genotype Mice Prions - genetics Sheep Tissue Distribution
Online-Zugang:	Volltext
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