Synthesis of N3-Substituted Uridine and Related Pyrimidine Nucleosides and Their Antinociceptive Effects in Mice

Seventy eight N3-substituted derivatives of uridine (1), thymidine (2), 2′-deoxyuridine (3), 6-azauridine (4), 2′,3′-O-isopropylideneuridine (5), and arabinofuranosyluracil (6) were synthesized and their antinociceptive effects were evaluated. N3-(2′,4′-Dimethoxyphenacyl)uridine (1l), N3-(2′,4′-dime...

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