Comparison of Large Versus Smaller Randomized Trials for Mental Health-Related Interventions

OBJECTIVE: The extent of disagreement between large and smaller randomized, controlled trials on mental health issues is unknown. The authors aimed to compare the results of large versus smaller trials on mental health-related interventions. METHOD: The authors screened 161 Cochrane and 254 Database...

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Veröffentlicht in:	The American journal of psychiatry 2005-03, Vol.162 (3), p.578-584
Hauptverfasser:	Contopoulos-Ioannidis, Despina G., Gilbody, Simon M., Trikalinos, Thomas A., Churchill, Rachel, Wahlbeck, Kristian, Ioannidis, John P.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - therapeutic use Benzodiazepines - therapeutic use Biological and medical sciences Child Clinical trials Comparative analysis Databases, Bibliographic - statistics & numerical data Day Care, Medical Humans Intelligence Medical sciences Mental Disorders - drug therapy Mental Disorders - therapy Mental health care Meta-Analysis as Topic Methodology. Experimentation Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Randomized Controlled Trials as Topic - standards Randomized Controlled Trials as Topic - statistics & numerical data Research Design - standards Research Design - statistics & numerical data Sample Size Schizophrenia - drug therapy Techniques and methods Treatment Outcome
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