Evaluation of Risk Factors in Predicting Coronary Artery Disease in Patients with Left Bundle Branch Block
This retrospective study examined whether classical risk factors for coronary artery disease (CAD) could also be used to predict CAD in patients with left bundle branch block (LBBB). Clinical and demographic features were studied in patients with/without CAD who presented with LBBB on their surface...
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Veröffentlicht in: | Journal of international medical research 2009-05, Vol.37 (3), p.822-827 |
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creator | Keles, T Durmaz, T Bektasoglu, G Turgut, O Manduz, S Sezer, H Tandogan, I |
description | This retrospective study examined whether classical risk factors for coronary artery disease (CAD) could also be used to predict CAD in patients with left bundle branch block (LBBB). Clinical and demographic features were studied in patients with/without CAD who presented with LBBB on their surface electrocardiograms and had undergone coronary angiography. Of the 312 patients with LBBB, 161 (51.6%) had CAD. Patients with CAD were more likely to be older, male, have CAD risk factors and to be taking acetylsalicylic acid or angiotensin-converting enzyme inhibitors. A model with six independent variables (family history, smoking, angina, advanced age, hypertension and total cholesterol levels) was statistically significant in predicting CAD in patients with LBBB, with an ability to predict patients with and without CAD of 87.1% and 90.6%, respectively. Predictors of CAD in patients with LBBB are consistent with classical risk factors and may help the accurate prediction of patients with CAD. |
doi_str_mv | 10.1177/147323000903700325 |
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Clinical and demographic features were studied in patients with/without CAD who presented with LBBB on their surface electrocardiograms and had undergone coronary angiography. Of the 312 patients with LBBB, 161 (51.6%) had CAD. Patients with CAD were more likely to be older, male, have CAD risk factors and to be taking acetylsalicylic acid or angiotensin-converting enzyme inhibitors. A model with six independent variables (family history, smoking, angina, advanced age, hypertension and total cholesterol levels) was statistically significant in predicting CAD in patients with LBBB, with an ability to predict patients with and without CAD of 87.1% and 90.6%, respectively. 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Clinical and demographic features were studied in patients with/without CAD who presented with LBBB on their surface electrocardiograms and had undergone coronary angiography. Of the 312 patients with LBBB, 161 (51.6%) had CAD. Patients with CAD were more likely to be older, male, have CAD risk factors and to be taking acetylsalicylic acid or angiotensin-converting enzyme inhibitors. A model with six independent variables (family history, smoking, angina, advanced age, hypertension and total cholesterol levels) was statistically significant in predicting CAD in patients with LBBB, with an ability to predict patients with and without CAD of 87.1% and 90.6%, respectively. Predictors of CAD in patients with LBBB are consistent with classical risk factors and may help the accurate prediction of patients with CAD.</description><subject>Aged</subject><subject>Bundle-Branch Block - complications</subject><subject>Confidence Intervals</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Demography</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Prognosis</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><issn>0300-0605</issn><issn>1473-2300</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFLAzEUhIMotlb_gAfJydval-xms3u0tVWhoEjvSzbNtmm3SU2yiv_e1BY8CJ7m8fhmYAahawJ3hHA-JBlPaQoAJaQcIKXsBPX3z2T_PUV9iJJADqyHLrxfA2Q0Z_Qc9UjJijLefbSefIi2E0Fbg22D37Tf4KmQwTqPtcGvTi20DNos8dg6a4T7wvcuqCgP2ivh1Q8V_coEjz91WOGZagIedWbRKjxywsgVHrVWbi7RWSNar66OOkDz6WQ-fkpmL4_P4_tZImlJQ5LlrGxqyblICRNCqpoSnnImYhsiJOFZJousTiXLozaNBOBUFQWDmpWcpQN0e4jdOfveKR-qrfZSta0wyna-ynnGCeV5BOkBlM5671RT7ZzexoYVgWo_cPV34Gi6OaZ39VYtfi3HRSMwPABeLFW1tp0zsex_kd_aGoJv</recordid><startdate>20090501</startdate><enddate>20090501</enddate><creator>Keles, T</creator><creator>Durmaz, T</creator><creator>Bektasoglu, G</creator><creator>Turgut, O</creator><creator>Manduz, S</creator><creator>Sezer, H</creator><creator>Tandogan, I</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090501</creationdate><title>Evaluation of Risk Factors in Predicting Coronary Artery Disease in Patients with Left Bundle Branch Block</title><author>Keles, T ; Durmaz, T ; Bektasoglu, G ; Turgut, O ; Manduz, S ; Sezer, H ; Tandogan, I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-4659fbc77a315aaceb217375a0301ac1744c84b3c56c84ffc0072e8850b59753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Bundle-Branch Block - complications</topic><topic>Confidence Intervals</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Demography</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Prognosis</topic><topic>Regression Analysis</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Keles, T</creatorcontrib><creatorcontrib>Durmaz, T</creatorcontrib><creatorcontrib>Bektasoglu, G</creatorcontrib><creatorcontrib>Turgut, O</creatorcontrib><creatorcontrib>Manduz, S</creatorcontrib><creatorcontrib>Sezer, H</creatorcontrib><creatorcontrib>Tandogan, I</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of international medical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Keles, T</au><au>Durmaz, T</au><au>Bektasoglu, G</au><au>Turgut, O</au><au>Manduz, S</au><au>Sezer, H</au><au>Tandogan, I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Risk Factors in Predicting Coronary Artery Disease in Patients with Left Bundle Branch Block</atitle><jtitle>Journal of international medical research</jtitle><addtitle>J Int Med Res</addtitle><date>2009-05-01</date><risdate>2009</risdate><volume>37</volume><issue>3</issue><spage>822</spage><epage>827</epage><pages>822-827</pages><issn>0300-0605</issn><eissn>1473-2300</eissn><abstract>This retrospective study examined whether classical risk factors for coronary artery disease (CAD) could also be used to predict CAD in patients with left bundle branch block (LBBB). Clinical and demographic features were studied in patients with/without CAD who presented with LBBB on their surface electrocardiograms and had undergone coronary angiography. Of the 312 patients with LBBB, 161 (51.6%) had CAD. Patients with CAD were more likely to be older, male, have CAD risk factors and to be taking acetylsalicylic acid or angiotensin-converting enzyme inhibitors. A model with six independent variables (family history, smoking, angina, advanced age, hypertension and total cholesterol levels) was statistically significant in predicting CAD in patients with LBBB, with an ability to predict patients with and without CAD of 87.1% and 90.6%, respectively. Predictors of CAD in patients with LBBB are consistent with classical risk factors and may help the accurate prediction of patients with CAD.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>19589265</pmid><doi>10.1177/147323000903700325</doi><tpages>6</tpages></addata></record> |
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subjects | Aged Bundle-Branch Block - complications Confidence Intervals Coronary Artery Disease - complications Coronary Artery Disease - diagnosis Demography Female Humans Male Prognosis Regression Analysis Risk Factors |
title | Evaluation of Risk Factors in Predicting Coronary Artery Disease in Patients with Left Bundle Branch Block |
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