Combination therapy with micafungin and amphotericin B for invasive pulmonary aspergillosis in an immunocompromised mouse model

Objectives Antifungal monotherapy with polyenes, azoles or echinocandins is not always effective for invasive pulmonary aspergillosis (IPA). The main purpose of this study was to evaluate the efficacy of a combination of micafungin and amphotericin B for the primary treatment of IPA in an immunocomp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antimicrobial chemotherapy 2009-08, Vol.64 (2), p.379-382
Hauptverfasser:	Nagasaki, Yoji, Eriguchi, Yoshihiro, Uchida, Yujiro, Miyake, Noriko, Maehara, Yoriko, Kadowaki, Masako, Harada, Mine, Akashi, Koichi, Shimono, Nobuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - therapeutic use Animals Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents - therapeutic use Antimicrobial agents Aspergillus fumigatus Aspergillus fumigatus - isolation & purification Biological and medical sciences Clinical outcomes Drug therapy Drug Therapy, Combination Echinocandins - therapeutic use Female fungal burden Fungal infections galactmannan index histopathology Human mycoses Immunocompromised Host Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Invasive Pulmonary Aspergillosis - drug therapy Kidney - pathology Lipopeptides - therapeutic use Lung - microbiology Lung - pathology Mannans - blood Medical sciences Mice Mice, Inbred ICR Mycoses Mycoses of the respiratory system Pharmacology Pharmacology. Drug treatments primary therapy Spleen - pathology Survival Analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!