Novel Hydrophobicity Ruler Approach for Determining the Octanol/Water Partition Coefficients of Very Hydrophobic Compounds via Their Polymer/Solvent Solution Distribution Coefficients

A novel hydrophobicity ruler approach for determining the octanol/water partition coefficients of very hydrophobic compounds is proposed, which is an indirect method that measures the polymer/solvent solution distribution coefficients (log K p/s) of reference and unknown compounds. The log K p/s val...

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