Peritransplant treatment with cobalt protoporphyrin attenuates chronic renal allograft rejection

Summary Allogen‐independent injury contributes to chronic rejection in renal allografts and heme oxygenase‐1 (HO‐1) has been shown to be protective in a number of settings. This study evaluated the effect of renal allograft recipient HO‐1 up‐regulation on chronic rejection in a rat model. Rat (F344...

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Veröffentlicht in:	Transplant international 2005-03, Vol.18 (3), p.341-349
Hauptverfasser:	Bédard, Eric L. R., Jiang, Jifu, Parry, Neil, Wang, Hao, Liu, Weihua, Garcia, Bertha, Kim, Peter, Chakrabarti, Subrata, Buelow, Roland, Zhong, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chronic Disease Cyclosporine - therapeutic use endothelin‐1 Enzyme Induction General aspects Graft Rejection - prevention & control heme oxygenase Heme Oxygenase (Decyclizing) - analysis Heme Oxygenase (Decyclizing) - biosynthesis Heme Oxygenase-1 Kidney - pathology Kidney Transplantation Medical sciences Nephrology. Urinary tract diseases Pharmacology. Drug treatments Protoporphyrins - therapeutic use rat Rats Rats, Inbred F344 Rats, Inbred Lew renal transplantation Transplantation, Homologous
Online-Zugang:	Volltext
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