The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons

Recent data have shown that the chemokine SDF-1 plays a critical role in several aspects of brain development such as cell migration and axon pathfinding. However, its potential function in the generation of axons and dendrites is poorly characterized. In order to better understand the role of SDF-1...

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Veröffentlicht in:	Journal of cell science 2005-03, Vol.118 (Pt 5), p.1071-1080
Hauptverfasser:	Pujol, Fabien, Kitabgi, Patrick, Boudin, Hélène
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - metabolism Blotting, Western Calcium - metabolism Cells, Cultured Chemokine CXCL12 Chemokines, CXC - physiology COS Cells Dendrites - metabolism Gene Expression Regulation, Developmental Green Fluorescent Proteins - metabolism Hippocampus - metabolism Immunoblotting Immunohistochemistry Microscopy, Phase-Contrast Neurons - metabolism Rats Receptors, CXCR4 - metabolism Signal Transduction Time Factors Transfection
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