Polycations. 19. The synthesis of symmetrical dicationic lipids with internal dimethylazonia functionalities separated by a spacer unit and pendant chains

Herein is reported the preparation of several series of symmetrical polyammonium salts that serve as cationic lipids or precursors thereof, and are structurally based on several series of parent diamines where dimethylazonia functionalities are present, separated by a central structural unit, and pe...

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Veröffentlicht in:	Chemistry and physics of lipids 2009-08, Vol.160 (2), p.105-108
Hauptverfasser:	Engel, Robert, Rizzo, JaimeLee Iolani, Montenegro, Diego, Leb, Jay, Coleman, Delroy, Hong, Carolyn, Jeanty, Herby, Thomas, Marie
Format:	Artikel
Sprache:	eng
Schlagworte:	Antihydrophobic effect Cationic lipid Diamines - chemistry Diol Hydrophobic and Hydrophilic Interactions Lipids - chemical synthesis Lipids - chemistry Polyamines - chemical synthesis Polyamines - chemistry Polycation Quaternary Ammonium Compounds - chemical synthesis Quaternary Ammonium Compounds - chemistry Quaternary ammonium salt Stereoisomerism Tetraol
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