Polymorphisms in XRCC1 Modify the Association between Polycyclic Aromatic Hydrocarbon-DNA Adducts, Cigarette Smoking, Dietary Antioxidants, and Breast Cancer Risk

The variability in DNA repair capacity of the general population may depend in part upon common variants in DNA repair genes. X-ray repair cross complementing group 1 ( XRCC1 ) is an important DNA base excision repair gene and exhibits polymorphic variation. Using the Long Island Breast Cancer Study...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2005-02, Vol.14 (2), p.336-342
Hauptverfasser:	JING SHEN, GAMMON, Marilie D, NEUGUT, Alfred I, SANTELLA, Regina M, TERRY, Mary Beth, LIANWEN WANG, QIAO WANG, FANGFANG ZHANG, TEITELBAUM, Susan L, ENG, Sybil M, SAGIV, Sharon K, GAUDET, Mia M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants Antioxidants - metabolism Biological and medical sciences Breast Cancer Risk Breast Neoplasms - epidemiology Breast Neoplasms - genetics Breast Neoplasms - metabolism Case-Control Studies Diet Dietary Supplements DNA Adducts - metabolism DNA-Binding Proteins - genetics Female Genotype Gynecology. Andrology. Obstetrics Humans Long Island Mammary gland diseases Medical sciences Middle Aged PAH-DNA adducts Polycyclic Aromatic Hydrocarbons - metabolism Polymorphism, Single Nucleotide Risk Factors Smoking - physiopathology Tumors X-ray Repair Cross Complementing Protein 1 XRCC1
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