Glial‐derived nexin, a differentially expressed gene during neuronal differentiation, transforms HEK cells into neuron‐like cells

Glial‐derived nexin (GDN) is a proteinase inhibitor secreted from glial cells and it can enhance neuronal function. However, its expression and function in neuronal differentiation are not, as yet, well‐known. In the present study, we analyzed glial‐derived nexin gene expression in dissociated neura...

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Veröffentlicht in:	International journal of developmental neuroscience 2005-02, Vol.23 (1), p.9-14
Hauptverfasser:	Lin, Hsingchi J., Shaffer, Kara M., Sun, Zairen, Jay, Gilbert, He, Wei‐wu, Ma, Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Protein Precursor - physiology Animals Blotting, Northern - methods Bromodeoxyuridine - metabolism Cell Differentiation - physiology Cells, Cultured Cloning, Molecular - methods Differential display Embryo, Mammalian Gene Expression - physiology Glial‐derived nexin Green Fluorescent Proteins - metabolism HEK Humans Immunohistochemistry - methods Indoles Mice Neural stem cells Neurogenesis Neurons - cytology Neurons - physiology Protease Nexins Receptors, Cell Surface - physiology Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - biosynthesis Stem Cells - physiology Transfection Transfection - methods Tubulin - metabolism
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