Self-Assembling Sequence-Adaptive Peptide Nucleic Acids

Several classes of nucleic acid analogs have been reported, but no synthetic informational polymer has yet proven responsive to selection pressures under enzyme-free conditions. Here, we introduce an oligomer family that efficiently self-assembles by means of reversible covalent anchoring of nucleob...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2009-07, Vol.325 (5936), p.73-77
Hauptverfasser:	Ura, Yasuyuki, Beierle, John M, Leman, Luke J, Orgel, Leslie E, Ghadiri, M. Reza
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - chemistry Amino acids Amino Acids - chemistry Base Pairing Base Sequence Biochemistry Biotinylation Deoxyribonucleic acid Dipeptides - chemistry DNA DNA - chemistry Melting Models, Molecular Molecular biology Molecular Structure Monomers Nucleic Acid Conformation Nucleic acids Nucleobases Oligomers Oligonucleotides Oligonucleotides - chemistry Peptide nucleic acids Peptide Nucleic Acids - chemistry Peptides Peptides - chemistry Ribonucleic acid RNA RNA - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!