Guidelines of care for cutaneous haemangiomas
Haemangiomas are common benign tumours of the vascular endothelium. They are extremely heterogenous clinically, with size, location and rate of proliferation having a significant effect on the risk of complications. The available evidence in the literature was evaluated using the grading system curr...
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Veröffentlicht in: | Annals of the Academy of Medicine, Singapore Singapore, 2005-01, Vol.34 (1), p.117-123 |
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creator | Chan, Y C Giam, Y C |
description | Haemangiomas are common benign tumours of the vascular endothelium. They are extremely heterogenous clinically, with size, location and rate of proliferation having a significant effect on the risk of complications.
The available evidence in the literature was evaluated using the grading system currently employed by the Ministry of Health, Singapore.
An uncomplicated haemangioma can be observed for spontaneous involution. However, some haemangiomas may be life- or function-threatening, or have associated structural anomalies. Corticosteroids may be used topically, intralesionally or systematically. Interferon alpha, vincristine and cyclophosphamide are therapeutic options for complicated haemangiomas which do not respond to corticosteroids. Vascular-specific pulse dye laser therapy may be considered for superficial haemangiomas, ulcerated haemangiomas or post-involution sequelae like telangiectasia. The mainstay of therapy for ulcerated haemangiomas is good local wound care, analgesics and treatment of secondary infection. A periorbital haemangioma that obstructs the visual axis or exerts pressure on the globe is an ocular emergency. Systemic corticosteroids and patching of the unaffected eye should be considered.
Medical practitioners should be aware of available therapeutic options for life- or function-threatening haemangiomas. Treatment must be individualised and referral to the relevant specialist should be considered in patients with complicated haemangiomas. |
doi_str_mv | 10.47102/annals-acadmedsg.V34N1p117 |
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The available evidence in the literature was evaluated using the grading system currently employed by the Ministry of Health, Singapore.
An uncomplicated haemangioma can be observed for spontaneous involution. However, some haemangiomas may be life- or function-threatening, or have associated structural anomalies. Corticosteroids may be used topically, intralesionally or systematically. Interferon alpha, vincristine and cyclophosphamide are therapeutic options for complicated haemangiomas which do not respond to corticosteroids. Vascular-specific pulse dye laser therapy may be considered for superficial haemangiomas, ulcerated haemangiomas or post-involution sequelae like telangiectasia. The mainstay of therapy for ulcerated haemangiomas is good local wound care, analgesics and treatment of secondary infection. A periorbital haemangioma that obstructs the visual axis or exerts pressure on the globe is an ocular emergency. Systemic corticosteroids and patching of the unaffected eye should be considered.
Medical practitioners should be aware of available therapeutic options for life- or function-threatening haemangiomas. Treatment must be individualised and referral to the relevant specialist should be considered in patients with complicated haemangiomas.</description><identifier>ISSN: 0304-4602</identifier><identifier>EISSN: 0304-4602</identifier><identifier>DOI: 10.47102/annals-acadmedsg.V34N1p117</identifier><identifier>PMID: 15726230</identifier><language>eng</language><publisher>Singapore</publisher><subject>Combined Modality Therapy - standards ; Diagnosis, Differential ; Hemangioma - diagnosis ; Hemangioma - therapy ; Humans ; Practice Guidelines as Topic ; Singapore ; Skin Neoplasms - diagnosis ; Skin Neoplasms - therapy</subject><ispartof>Annals of the Academy of Medicine, Singapore, 2005-01, Vol.34 (1), p.117-123</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-6dc3222574ff48e824383088c03b6e54c282fd8c1eaa5eba485b5a25c5f41353</citedby><cites>FETCH-LOGICAL-c319t-6dc3222574ff48e824383088c03b6e54c282fd8c1eaa5eba485b5a25c5f41353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15726230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Y C</creatorcontrib><creatorcontrib>Giam, Y C</creatorcontrib><title>Guidelines of care for cutaneous haemangiomas</title><title>Annals of the Academy of Medicine, Singapore</title><addtitle>Ann Acad Med Singapore</addtitle><description>Haemangiomas are common benign tumours of the vascular endothelium. They are extremely heterogenous clinically, with size, location and rate of proliferation having a significant effect on the risk of complications.
The available evidence in the literature was evaluated using the grading system currently employed by the Ministry of Health, Singapore.
An uncomplicated haemangioma can be observed for spontaneous involution. However, some haemangiomas may be life- or function-threatening, or have associated structural anomalies. Corticosteroids may be used topically, intralesionally or systematically. Interferon alpha, vincristine and cyclophosphamide are therapeutic options for complicated haemangiomas which do not respond to corticosteroids. Vascular-specific pulse dye laser therapy may be considered for superficial haemangiomas, ulcerated haemangiomas or post-involution sequelae like telangiectasia. The mainstay of therapy for ulcerated haemangiomas is good local wound care, analgesics and treatment of secondary infection. A periorbital haemangioma that obstructs the visual axis or exerts pressure on the globe is an ocular emergency. Systemic corticosteroids and patching of the unaffected eye should be considered.
Medical practitioners should be aware of available therapeutic options for life- or function-threatening haemangiomas. Treatment must be individualised and referral to the relevant specialist should be considered in patients with complicated haemangiomas.</description><subject>Combined Modality Therapy - standards</subject><subject>Diagnosis, Differential</subject><subject>Hemangioma - diagnosis</subject><subject>Hemangioma - therapy</subject><subject>Humans</subject><subject>Practice Guidelines as Topic</subject><subject>Singapore</subject><subject>Skin Neoplasms - diagnosis</subject><subject>Skin Neoplasms - therapy</subject><issn>0304-4602</issn><issn>0304-4602</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkM1Lw0AQxRdRbK3-CxIQvG3dz2TFkxStQtFL8bpMNrM1ki93k4P_vdGU6mkG5r15jx8hV5wtVcaZuIGmgSpScFDUWMTd8k2qF95xnh2ROZNMUZUycfxvn5GzGD8YUxkT6SmZcZ2JVEg2J3Q9lAVWZYMxaX3iIGDi25C4oYcG2yEm74A1NLuyrSGekxM_RuPFfi7I9vFhu3qim9f18-p-Q53ktz1NCyeFEDpT3iuDRihpJDPGMZmnqJUTRvjCOI4AGnNQRucahHbaKy61XJDr6W0X2s8BY2_rMjqsqqmSTTOlpTY_wrtJ6EIbY0Bvu1DWEL4sZ_YXlp1g2QMse4A1ui_3MUM-3v68ezryG6dsaqM</recordid><startdate>20050101</startdate><enddate>20050101</enddate><creator>Chan, Y C</creator><creator>Giam, Y C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050101</creationdate><title>Guidelines of care for cutaneous haemangiomas</title><author>Chan, Y C ; Giam, Y C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-6dc3222574ff48e824383088c03b6e54c282fd8c1eaa5eba485b5a25c5f41353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Combined Modality Therapy - standards</topic><topic>Diagnosis, Differential</topic><topic>Hemangioma - diagnosis</topic><topic>Hemangioma - therapy</topic><topic>Humans</topic><topic>Practice Guidelines as Topic</topic><topic>Singapore</topic><topic>Skin Neoplasms - diagnosis</topic><topic>Skin Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Y C</creatorcontrib><creatorcontrib>Giam, Y C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the Academy of Medicine, Singapore</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Y C</au><au>Giam, Y C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Guidelines of care for cutaneous haemangiomas</atitle><jtitle>Annals of the Academy of Medicine, Singapore</jtitle><addtitle>Ann Acad Med Singapore</addtitle><date>2005-01-01</date><risdate>2005</risdate><volume>34</volume><issue>1</issue><spage>117</spage><epage>123</epage><pages>117-123</pages><issn>0304-4602</issn><eissn>0304-4602</eissn><abstract>Haemangiomas are common benign tumours of the vascular endothelium. They are extremely heterogenous clinically, with size, location and rate of proliferation having a significant effect on the risk of complications.
The available evidence in the literature was evaluated using the grading system currently employed by the Ministry of Health, Singapore.
An uncomplicated haemangioma can be observed for spontaneous involution. However, some haemangiomas may be life- or function-threatening, or have associated structural anomalies. Corticosteroids may be used topically, intralesionally or systematically. Interferon alpha, vincristine and cyclophosphamide are therapeutic options for complicated haemangiomas which do not respond to corticosteroids. Vascular-specific pulse dye laser therapy may be considered for superficial haemangiomas, ulcerated haemangiomas or post-involution sequelae like telangiectasia. The mainstay of therapy for ulcerated haemangiomas is good local wound care, analgesics and treatment of secondary infection. A periorbital haemangioma that obstructs the visual axis or exerts pressure on the globe is an ocular emergency. Systemic corticosteroids and patching of the unaffected eye should be considered.
Medical practitioners should be aware of available therapeutic options for life- or function-threatening haemangiomas. Treatment must be individualised and referral to the relevant specialist should be considered in patients with complicated haemangiomas.</abstract><cop>Singapore</cop><pmid>15726230</pmid><doi>10.47102/annals-acadmedsg.V34N1p117</doi><tpages>7</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
subjects | Combined Modality Therapy - standards Diagnosis, Differential Hemangioma - diagnosis Hemangioma - therapy Humans Practice Guidelines as Topic Singapore Skin Neoplasms - diagnosis Skin Neoplasms - therapy |
title | Guidelines of care for cutaneous haemangiomas |
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