Hepatitis B vaccination and central nervous system demyelination: an immunological approach
Demyelination events or multiple sclerosis following hepatitis B virus (HBV) vaccination have been reported. We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in te...
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| Veröffentlicht in: | Journal of autoimmunity 2005-02, Vol.24 (1), p.33-37 |
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| container_title | Journal of autoimmunity |
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| creator | Piaggio, E. Ben Younes, A. Desbois, S. Gout, O. Tourbah, A. Lyon-Caen, O. Liblau, R.S. |
| description | Demyelination events or multiple sclerosis following hepatitis B virus (HBV) vaccination have been reported. We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in terms of T-cell proliferation or cytokine production between these groups and may help to allay concerns that HBV vaccination might trigger a deleterious immune response. |
| doi_str_mv | 10.1016/j.jaut.2004.11.007 |
| format | Article |
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We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in terms of T-cell proliferation or cytokine production between these groups and may help to allay concerns that HBV vaccination might trigger a deleterious immune response.</description><identifier>ISSN: 0896-8411</identifier><identifier>EISSN: 1095-9157</identifier><identifier>DOI: 10.1016/j.jaut.2004.11.007</identifier><identifier>PMID: 15725574</identifier><language>eng</language><publisher>London: Elsevier Ltd</publisher><subject>Adult ; Biological and medical sciences ; Cell Proliferation ; Central Nervous System - immunology ; Central Nervous System - pathology ; CNS demyelination ; Cytokines - biosynthesis ; Cytokines - immunology ; Cytokines - metabolism ; Demyelinating Autoimmune Diseases, CNS - etiology ; Demyelinating Autoimmune Diseases, CNS - immunology ; Demyelinating Autoimmune Diseases, CNS - pathology ; Female ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; General aspects ; Hepatitis B - immunology ; Hepatitis B vaccination ; Hepatitis B Vaccines - adverse effects ; Hepatitis B Vaccines - immunology ; Hepatitis B virus ; Hepatitis B virus - immunology ; Humans ; IFN-γ ; IL-5 ; Immunopathology ; Male ; Medical sciences ; Middle Aged ; Multiple sclerosis ; Myelin Sheath - metabolism ; T-Lymphocytes - cytology ; T-Lymphocytes - immunology ; T-Lymphocytes - metabolism ; Vaccination - adverse effects</subject><ispartof>Journal of autoimmunity, 2005-02, Vol.24 (1), p.33-37</ispartof><rights>2004 Elsevier Ltd</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-3924f9d9bf24e8b9b33d7bb11554a40acb614afe41adb4c2a29612d7d081f5fe3</citedby><cites>FETCH-LOGICAL-c446t-3924f9d9bf24e8b9b33d7bb11554a40acb614afe41adb4c2a29612d7d081f5fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaut.2004.11.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16581777$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15725574$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Piaggio, E.</creatorcontrib><creatorcontrib>Ben Younes, A.</creatorcontrib><creatorcontrib>Desbois, S.</creatorcontrib><creatorcontrib>Gout, O.</creatorcontrib><creatorcontrib>Tourbah, A.</creatorcontrib><creatorcontrib>Lyon-Caen, O.</creatorcontrib><creatorcontrib>Liblau, R.S.</creatorcontrib><title>Hepatitis B vaccination and central nervous system demyelination: an immunological approach</title><title>Journal of autoimmunity</title><addtitle>J Autoimmun</addtitle><description>Demyelination events or multiple sclerosis following hepatitis B virus (HBV) vaccination have been reported. We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in terms of T-cell proliferation or cytokine production between these groups and may help to allay concerns that HBV vaccination might trigger a deleterious immune response.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cell Proliferation</subject><subject>Central Nervous System - immunology</subject><subject>Central Nervous System - pathology</subject><subject>CNS demyelination</subject><subject>Cytokines - biosynthesis</subject><subject>Cytokines - immunology</subject><subject>Cytokines - metabolism</subject><subject>Demyelinating Autoimmune Diseases, CNS - etiology</subject><subject>Demyelinating Autoimmune Diseases, CNS - immunology</subject><subject>Demyelinating Autoimmune Diseases, CNS - pathology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>General aspects</subject><subject>Hepatitis B - immunology</subject><subject>Hepatitis B vaccination</subject><subject>Hepatitis B Vaccines - adverse effects</subject><subject>Hepatitis B Vaccines - immunology</subject><subject>Hepatitis B virus</subject><subject>Hepatitis B virus - immunology</subject><subject>Humans</subject><subject>IFN-γ</subject><subject>IL-5</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multiple sclerosis</subject><subject>Myelin Sheath - metabolism</subject><subject>T-Lymphocytes - cytology</subject><subject>T-Lymphocytes - immunology</subject><subject>T-Lymphocytes - metabolism</subject><subject>Vaccination - adverse effects</subject><issn>0896-8411</issn><issn>1095-9157</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFu1DAURS0EokPhB1igbGCX1M-x4xixKRXQSpXYtCsWlmO_gEeJM9jJSPP3OJpI3dGVZfm866t3CHkPtAIKzdW-2ptlrhilvAKoKJUvyA6oEqUCIV-SHW1VU7Yc4IK8SWlPKYAQ4jW5yM9MCMl35NctHszsZ5-Kr8XRWOtDvk6hMMEVFsMczVAEjMdpSUU6pRnHwuF4wmEDP2ey8OO4hGmYfnubcXM4xMnYP2_Jq94MCd9t5yV5_P7t4ea2vP_54-7m-r60nDdzWSvGe-VU1zOObae6unay69au3HBqbNcANz1yMK7jlhmmGmBOOtpCL3qsL8mnc27-9u-CadajTxaHwQTMtXUjuagpZc-CoFpFFaufB6Wo64aqDLIzaOOUUsReH6IfTTxpoHqVpPd6laRXSRpAZ0l56MOWvnQjuqeRzUoGPm6ASXmhfTTB-vTENaIFKdegL2cO83aPHqNO1mOw6HxEO2s3-f_1-Ad4tbEg</recordid><startdate>20050201</startdate><enddate>20050201</enddate><creator>Piaggio, E.</creator><creator>Ben Younes, A.</creator><creator>Desbois, S.</creator><creator>Gout, O.</creator><creator>Tourbah, A.</creator><creator>Lyon-Caen, O.</creator><creator>Liblau, R.S.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7U9</scope><scope>7X8</scope></search><sort><creationdate>20050201</creationdate><title>Hepatitis B vaccination and central nervous system demyelination: an immunological approach</title><author>Piaggio, E. ; Ben Younes, A. ; Desbois, S. ; Gout, O. ; Tourbah, A. ; Lyon-Caen, O. ; Liblau, R.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-3924f9d9bf24e8b9b33d7bb11554a40acb614afe41adb4c2a29612d7d081f5fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cell Proliferation</topic><topic>Central Nervous System - immunology</topic><topic>Central Nervous System - pathology</topic><topic>CNS demyelination</topic><topic>Cytokines - biosynthesis</topic><topic>Cytokines - immunology</topic><topic>Cytokines - metabolism</topic><topic>Demyelinating Autoimmune Diseases, CNS - etiology</topic><topic>Demyelinating Autoimmune Diseases, CNS - immunology</topic><topic>Demyelinating Autoimmune Diseases, CNS - pathology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>General aspects</topic><topic>Hepatitis B - immunology</topic><topic>Hepatitis B vaccination</topic><topic>Hepatitis B Vaccines - adverse effects</topic><topic>Hepatitis B Vaccines - immunology</topic><topic>Hepatitis B virus</topic><topic>Hepatitis B virus - immunology</topic><topic>Humans</topic><topic>IFN-γ</topic><topic>IL-5</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multiple sclerosis</topic><topic>Myelin Sheath - metabolism</topic><topic>T-Lymphocytes - cytology</topic><topic>T-Lymphocytes - immunology</topic><topic>T-Lymphocytes - metabolism</topic><topic>Vaccination - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Piaggio, E.</creatorcontrib><creatorcontrib>Ben Younes, A.</creatorcontrib><creatorcontrib>Desbois, S.</creatorcontrib><creatorcontrib>Gout, O.</creatorcontrib><creatorcontrib>Tourbah, A.</creatorcontrib><creatorcontrib>Lyon-Caen, O.</creatorcontrib><creatorcontrib>Liblau, R.S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of autoimmunity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Piaggio, E.</au><au>Ben Younes, A.</au><au>Desbois, S.</au><au>Gout, O.</au><au>Tourbah, A.</au><au>Lyon-Caen, O.</au><au>Liblau, R.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatitis B vaccination and central nervous system demyelination: an immunological approach</atitle><jtitle>Journal of autoimmunity</jtitle><addtitle>J Autoimmun</addtitle><date>2005-02-01</date><risdate>2005</risdate><volume>24</volume><issue>1</issue><spage>33</spage><epage>37</epage><pages>33-37</pages><issn>0896-8411</issn><eissn>1095-9157</eissn><abstract>Demyelination events or multiple sclerosis following hepatitis B virus (HBV) vaccination have been reported. We therefore compared the T-cell response to HBsAg in patients with CNS demyelination following HBV vaccination and in HBV-vaccinated healthy individuals. Our data showed no differences in terms of T-cell proliferation or cytokine production between these groups and may help to allay concerns that HBV vaccination might trigger a deleterious immune response.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><pmid>15725574</pmid><doi>10.1016/j.jaut.2004.11.007</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Biological and medical sciences Cell Proliferation Central Nervous System - immunology Central Nervous System - pathology CNS demyelination Cytokines - biosynthesis Cytokines - immunology Cytokines - metabolism Demyelinating Autoimmune Diseases, CNS - etiology Demyelinating Autoimmune Diseases, CNS - immunology Demyelinating Autoimmune Diseases, CNS - pathology Female Fundamental and applied biological sciences. Psychology Fundamental immunology General aspects Hepatitis B - immunology Hepatitis B vaccination Hepatitis B Vaccines - adverse effects Hepatitis B Vaccines - immunology Hepatitis B virus Hepatitis B virus - immunology Humans IFN-γ IL-5 Immunopathology Male Medical sciences Middle Aged Multiple sclerosis Myelin Sheath - metabolism T-Lymphocytes - cytology T-Lymphocytes - immunology T-Lymphocytes - metabolism Vaccination - adverse effects |
| title | Hepatitis B vaccination and central nervous system demyelination: an immunological approach |
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