Transcriptional regulation through RfaH contributes to intestinal colonization by Escherichia coli

The Escherichia coli regulatory protein RfaH contributes to efficient colonization of the mouse gut. Extraintestinal pathogenic (ExPEC) as well as non-pathogenic probiotic E. coli strains rapidly outcompeted their isogenic rfaH mutants following oral mixed infections. LPS-core and O-antigen side-cha...

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Veröffentlicht in:	FEMS microbiology letters 2005-03, Vol.244 (1), p.173-180
Hauptverfasser:	Nagy, Gábor, Dobrindt, Ulrich, Grozdanov, Lubomir, Hacker, Jörg, Emődy, Levente
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Bacteria Bacterial Adhesion Bacteriology Base Sequence Bile Acids and Salts - pharmacology Bile salt resistance Bile salts Biological and medical sciences Capsular polysaccharides Cell Line Chains Colon Colonization Core loss Deep-rough LPS DNA, Bacterial - genetics E coli Epithelial cells Escherichia coli Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - pathogenicity Escherichia coli - physiology Escherichia coli Proteins - genetics Escherichia coli Proteins - physiology Female Fundamental and applied biological sciences. Psychology Gene Deletion Gene regulation Genes, Bacterial Genetics Glucosyltransferases - genetics Glucosyltransferases - physiology Group II capsules Humans Intestine Intestines - microbiology Lipopolysaccharides Lipopolysaccharides - metabolism Mice Microbiology Motility, taxis Mutants Mutation Novobiocin - pharmacology Peptide Elongation Factors - genetics Peptide Elongation Factors - physiology Polysaccharides Probiotics RfaH Salts Sodium Dodecyl Sulfate - pharmacology Synthesis Trans-Activators - genetics Trans-Activators - physiology Transcription Transcription, Genetic Virulence Virulence - genetics Virulence factors
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