XAF1 mRNA expression improves progression-free and overall survival for patients with advanced bladder cancer treated with neoadjuvant chemotherapy

Abstract Purpose The aim of this study was to investigate whether mRNA expression of the apoptosis-associated genes, XAF1 and XIAP, in bladder cancer patients correlates with response to neoadjuvant treatment. Methods Gene expression was analyzed by a real-time quantitative PCR method in paired samp...

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Veröffentlicht in:	Urologic oncology 2009-07, Vol.27 (4), p.382-390
Hauptverfasser:	Pinho, Marcos B., MSc, Costas, Fernanda, B.S, Sellos, João, B.S, Dienstmann, Rodrigo, M.D, Andrade, Patricia B., M.D, Herchenhorn, Daniel, M.D, Peixoto, Fábio Afonso, M.D, Santos, Valdelice O., R.N, Small, Isabele A., MSc, Guimarães, Denise P., M.D., Ph.D, Ferreira, Carlos G., M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Agents - therapeutic use Biological and medical sciences Bladder carcinoma Chemotherapy, Adjuvant - methods Cisplatin - pharmacology Deoxycytidine - analogs & derivatives Deoxycytidine - pharmacology Disease-Free Survival Female Gene Expression Regulation, Neoplastic Humans Intracellular Signaling Peptides and Proteins Male Medical sciences Middle Aged mRNA Neoplasm Proteins - biosynthesis Neoplasm Proteins - physiology Nephrology. Urinary tract diseases Outcome Prognosis Treatment Outcome Tumors Tumors of the urinary system Urinary Bladder Neoplasms - drug therapy Urinary Bladder Neoplasms - surgery Urinary tract. Prostate gland Urology XAF1
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