Smoking Is a Risk Factor for Incisional Hernia

HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN...

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Veröffentlicht in:Archives of surgery (Chicago. 1960) 2005-02, Vol.140 (2), p.119-123
Hauptverfasser: Sørensen, Lars Tue, Hemmingsen, Ulla B, Kirkeby, Lene T, Kallehave, Finn, Jørgensen, Lars Nannestad
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container_end_page 123
container_issue 2
container_start_page 119
container_title Archives of surgery (Chicago. 1960)
container_volume 140
creator Sørensen, Lars Tue
Hemmingsen, Ulla B
Kirkeby, Lene T
Kallehave, Finn
Jørgensen, Lars Nannestad
description HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparotomy for gastrointestinal disease. Variables predictive for incisional hernia were assessed by multiple regression analysis. SETTING Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. PATIENTS All 916 patients undergoing laparotomy from 1997 through 1998. Surgeons performed clinical examination in 310 patients; patients who failed to meet for examination, died, or were lost to follow-up were excluded. MAIN OUTCOME MEASURES Thirty-four variables related to patient history, preoperative clinical condition, operative severity and findings, and the surgeon’s training. RESULTS The incidence of incisional hernia was 26% (81/310). Smokers had a 4-fold higher risk of incisional hernia (odds ratio [OR], 3.93 [95% confidence interval (CI), 1.82-8.49]) independent of other risk factors and confounders. Relaparotomy was the strongest factor associated with hernia (OR, 5.89 [95% CI, 1.78-19.48]). Other risk factors were postoperative wound complications (OR, 3.91 [95% CI, 1.99-7.66]), age (OR, 1.04 [95% CI, 1.02-1.06]), and male sex (OR, 2.17 [95% CI, 1.21-3.91]). CONCLUSION Smoking is a significant risk factor for incisional hernia in line with relaparotomy, postoperative wound complications, older age, and male sex.Arch Surg. 2005;140:119-123-->
doi_str_mv 10.1001/archsurg.140.2.119
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Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparotomy for gastrointestinal disease. Variables predictive for incisional hernia were assessed by multiple regression analysis. SETTING Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. PATIENTS All 916 patients undergoing laparotomy from 1997 through 1998. Surgeons performed clinical examination in 310 patients; patients who failed to meet for examination, died, or were lost to follow-up were excluded. MAIN OUTCOME MEASURES Thirty-four variables related to patient history, preoperative clinical condition, operative severity and findings, and the surgeon’s training. RESULTS The incidence of incisional hernia was 26% (81/310). Smokers had a 4-fold higher risk of incisional hernia (odds ratio [OR], 3.93 [95% confidence interval (CI), 1.82-8.49]) independent of other risk factors and confounders. Relaparotomy was the strongest factor associated with hernia (OR, 5.89 [95% CI, 1.78-19.48]). Other risk factors were postoperative wound complications (OR, 3.91 [95% CI, 1.99-7.66]), age (OR, 1.04 [95% CI, 1.02-1.06]), and male sex (OR, 2.17 [95% CI, 1.21-3.91]). CONCLUSION Smoking is a significant risk factor for incisional hernia in line with relaparotomy, postoperative wound complications, older age, and male sex.Arch Surg. 2005;140:119-123--&gt;</description><identifier>ISSN: 0004-0010</identifier><identifier>ISSN: 2168-6254</identifier><identifier>EISSN: 1538-3644</identifier><identifier>EISSN: 2168-6262</identifier><identifier>DOI: 10.1001/archsurg.140.2.119</identifier><identifier>PMID: 15723991</identifier><identifier>CODEN: ARSUAX</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Aged ; Biological and medical sciences ; Clinical outcomes ; Female ; General aspects ; Hernia, Abdominal - epidemiology ; Hernia, Abdominal - physiopathology ; Hernias ; Humans ; Laparotomy ; Logistic Models ; Male ; Medical sciences ; Middle Aged ; Postoperative Complications - epidemiology ; Risk Factors ; Smoking ; Smoking - adverse effects ; Smoking - physiopathology ; Studies ; Tobacco, tobacco smoking ; Toxicology ; Wound Healing - physiology</subject><ispartof>Archives of surgery (Chicago. 1960), 2005-02, Vol.140 (2), p.119-123</ispartof><rights>2005 INIST-CNRS</rights><rights>Copyright American Medical Association Feb 2005</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a376t-d5c553c8b35ee56c76ededa4f8b7b45202829c982c7fcdaa1128ef83799f23393</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jamasurgery/articlepdf/10.1001/archsurg.140.2.119$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/archsurg.140.2.119$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,780,784,3340,27924,27925,76489,76492</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=16562009$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15723991$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sørensen, Lars Tue</creatorcontrib><creatorcontrib>Hemmingsen, Ulla B</creatorcontrib><creatorcontrib>Kirkeby, Lene T</creatorcontrib><creatorcontrib>Kallehave, Finn</creatorcontrib><creatorcontrib>Jørgensen, Lars Nannestad</creatorcontrib><title>Smoking Is a Risk Factor for Incisional Hernia</title><title>Archives of surgery (Chicago. 1960)</title><addtitle>Arch Surg</addtitle><description>HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparotomy for gastrointestinal disease. Variables predictive for incisional hernia were assessed by multiple regression analysis. SETTING Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. PATIENTS All 916 patients undergoing laparotomy from 1997 through 1998. Surgeons performed clinical examination in 310 patients; patients who failed to meet for examination, died, or were lost to follow-up were excluded. MAIN OUTCOME MEASURES Thirty-four variables related to patient history, preoperative clinical condition, operative severity and findings, and the surgeon’s training. RESULTS The incidence of incisional hernia was 26% (81/310). Smokers had a 4-fold higher risk of incisional hernia (odds ratio [OR], 3.93 [95% confidence interval (CI), 1.82-8.49]) independent of other risk factors and confounders. Relaparotomy was the strongest factor associated with hernia (OR, 5.89 [95% CI, 1.78-19.48]). Other risk factors were postoperative wound complications (OR, 3.91 [95% CI, 1.99-7.66]), age (OR, 1.04 [95% CI, 1.02-1.06]), and male sex (OR, 2.17 [95% CI, 1.21-3.91]). CONCLUSION Smoking is a significant risk factor for incisional hernia in line with relaparotomy, postoperative wound complications, older age, and male sex.Arch Surg. 2005;140:119-123--&gt;</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Clinical outcomes</subject><subject>Female</subject><subject>General aspects</subject><subject>Hernia, Abdominal - epidemiology</subject><subject>Hernia, Abdominal - physiopathology</subject><subject>Hernias</subject><subject>Humans</subject><subject>Laparotomy</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Postoperative Complications - epidemiology</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Smoking - adverse effects</subject><subject>Smoking - physiopathology</subject><subject>Studies</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><subject>Wound Healing - physiology</subject><issn>0004-0010</issn><issn>2168-6254</issn><issn>1538-3644</issn><issn>2168-6262</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE1LAzEQhoMotlZ_gB5kEfS2az42m-QoxWqhIPhxDrPZbN12P2rSPfjvTelqwcMwA_PMy_AgdEVwQjAm9-DMp-_dMiEpTmhCiDpCY8KZjFmWpsdojDFO40DiETrzfhUmKhU9RSPCBWVKkTFK3ppuXbXLaO4jiF4rv45mYLadi8pQ89ZUvupaqKNn69oKztFJCbW3F0OfoI_Z4_v0OV68PM2nD4sYmMi2ccEN58zInHFreWZEZgtbQFrKXOQpp5hKqoyS1IjSFAAkPGZLyYRSJWVMsQm62-duXPfVW7_VTeWNrWtobdd7nYk0VUKwAN78A1dd78LDXlNGOedYyQDRPWRc572zpd64qgH3rQnWO5X6V6UOKjXVQWU4uh6S-7yxxeFkcBeA2wEAb6AuHexsHbiMZxTjXdDlnoMG_rYcS8YE-wHI34QV</recordid><startdate>20050201</startdate><enddate>20050201</enddate><creator>Sørensen, Lars Tue</creator><creator>Hemmingsen, Ulla B</creator><creator>Kirkeby, Lene T</creator><creator>Kallehave, Finn</creator><creator>Jørgensen, Lars Nannestad</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20050201</creationdate><title>Smoking Is a Risk Factor for Incisional Hernia</title><author>Sørensen, Lars Tue ; Hemmingsen, Ulla B ; Kirkeby, Lene T ; Kallehave, Finn ; Jørgensen, Lars Nannestad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a376t-d5c553c8b35ee56c76ededa4f8b7b45202829c982c7fcdaa1128ef83799f23393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Clinical outcomes</topic><topic>Female</topic><topic>General aspects</topic><topic>Hernia, Abdominal - epidemiology</topic><topic>Hernia, Abdominal - physiopathology</topic><topic>Hernias</topic><topic>Humans</topic><topic>Laparotomy</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Postoperative Complications - epidemiology</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Smoking - adverse effects</topic><topic>Smoking - physiopathology</topic><topic>Studies</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><topic>Wound Healing - physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Sørensen, Lars Tue</creatorcontrib><creatorcontrib>Hemmingsen, Ulla B</creatorcontrib><creatorcontrib>Kirkeby, Lene T</creatorcontrib><creatorcontrib>Kallehave, Finn</creatorcontrib><creatorcontrib>Jørgensen, Lars Nannestad</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of surgery (Chicago. 1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sørensen, Lars Tue</au><au>Hemmingsen, Ulla B</au><au>Kirkeby, Lene T</au><au>Kallehave, Finn</au><au>Jørgensen, Lars Nannestad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Smoking Is a Risk Factor for Incisional Hernia</atitle><jtitle>Archives of surgery (Chicago. 1960)</jtitle><addtitle>Arch Surg</addtitle><date>2005-02-01</date><risdate>2005</risdate><volume>140</volume><issue>2</issue><spage>119</spage><epage>123</epage><pages>119-123</pages><issn>0004-0010</issn><issn>2168-6254</issn><eissn>1538-3644</eissn><eissn>2168-6262</eissn><coden>ARSUAX</coden><abstract>HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparotomy for gastrointestinal disease. Variables predictive for incisional hernia were assessed by multiple regression analysis. SETTING Department of Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. PATIENTS All 916 patients undergoing laparotomy from 1997 through 1998. Surgeons performed clinical examination in 310 patients; patients who failed to meet for examination, died, or were lost to follow-up were excluded. MAIN OUTCOME MEASURES Thirty-four variables related to patient history, preoperative clinical condition, operative severity and findings, and the surgeon’s training. RESULTS The incidence of incisional hernia was 26% (81/310). Smokers had a 4-fold higher risk of incisional hernia (odds ratio [OR], 3.93 [95% confidence interval (CI), 1.82-8.49]) independent of other risk factors and confounders. Relaparotomy was the strongest factor associated with hernia (OR, 5.89 [95% CI, 1.78-19.48]). Other risk factors were postoperative wound complications (OR, 3.91 [95% CI, 1.99-7.66]), age (OR, 1.04 [95% CI, 1.02-1.06]), and male sex (OR, 2.17 [95% CI, 1.21-3.91]). CONCLUSION Smoking is a significant risk factor for incisional hernia in line with relaparotomy, postoperative wound complications, older age, and male sex.Arch Surg. 2005;140:119-123--&gt;</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>15723991</pmid><doi>10.1001/archsurg.140.2.119</doi><tpages>5</tpages></addata></record>
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subjects Aged
Biological and medical sciences
Clinical outcomes
Female
General aspects
Hernia, Abdominal - epidemiology
Hernia, Abdominal - physiopathology
Hernias
Humans
Laparotomy
Logistic Models
Male
Medical sciences
Middle Aged
Postoperative Complications - epidemiology
Risk Factors
Smoking
Smoking - adverse effects
Smoking - physiopathology
Studies
Tobacco, tobacco smoking
Toxicology
Wound Healing - physiology
title Smoking Is a Risk Factor for Incisional Hernia
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