Trypanosoma irwini n. sp (Sarcomastigophora: Trypanosomatidae) from the koala (Phascolarctos cinereus)
The morphology and genetic characterization of a new species of trypanosome infecting koalas (Phascolarctos cinereus) are described. Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this trypanosome species to be genetically distinct...
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| Veröffentlicht in: | Parasitology 2009-07, Vol.136 (8), p.875-885 |
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| creator | McINNES, L. M. GILLETT, A. RYAN, U. M. AUSTEN, J. CAMPBELL, R. S. F. HANGER, J. REID, S. A. |
| description | The morphology and genetic characterization of a new species of trypanosome infecting koalas (Phascolarctos cinereus) are described. Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this trypanosome species to be genetically distinct and most similar to Trypanosoma bennetti, an avian trypanosome with a genetic distance of 0·9% at the 18S rDNA and 10·7% at the gGAPDH locus. The trypanosome was detected by 18S rDNA PCR in the blood samples of 26 out of 68 (38·2%) koalas studied. The aetiological role of trypanosomes in koala disease is currently poorly defined, although infection with these parasites has been associated with severe clinical signs in a number of koalas. Based on biological and genetic characterization data, this trypanosome species infecting koalas is proposed to be a new species Trypanosome irwini n. sp. |
| doi_str_mv | 10.1017/S0031182009006313 |
| format | Article |
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M. ; GILLETT, A. ; RYAN, U. M. ; AUSTEN, J. ; CAMPBELL, R. S. F. ; HANGER, J. ; REID, S. A.</creator><creatorcontrib>McINNES, L. M. ; GILLETT, A. ; RYAN, U. M. ; AUSTEN, J. ; CAMPBELL, R. S. F. ; HANGER, J. ; REID, S. A.</creatorcontrib><description>The morphology and genetic characterization of a new species of trypanosome infecting koalas (Phascolarctos cinereus) are described. Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this trypanosome species to be genetically distinct and most similar to Trypanosoma bennetti, an avian trypanosome with a genetic distance of 0·9% at the 18S rDNA and 10·7% at the gGAPDH locus. The trypanosome was detected by 18S rDNA PCR in the blood samples of 26 out of 68 (38·2%) koalas studied. The aetiological role of trypanosomes in koala disease is currently poorly defined, although infection with these parasites has been associated with severe clinical signs in a number of koalas. Based on biological and genetic characterization data, this trypanosome species infecting koalas is proposed to be a new species Trypanosome irwini n. sp.</description><identifier>ISSN: 0031-1820</identifier><identifier>EISSN: 1469-8161</identifier><identifier>DOI: 10.1017/S0031182009006313</identifier><identifier>PMID: 19570316</identifier><identifier>CODEN: PARAAE</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>18S rDNA ; Animals ; Biological and medical sciences ; Female ; Fundamental and applied biological sciences. Psychology ; General aspects ; General aspects and techniques. Study of several systematic groups. 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The trypanosome was detected by 18S rDNA PCR in the blood samples of 26 out of 68 (38·2%) koalas studied. The aetiological role of trypanosomes in koala disease is currently poorly defined, although infection with these parasites has been associated with severe clinical signs in a number of koalas. Based on biological and genetic characterization data, this trypanosome species infecting koalas is proposed to be a new species Trypanosome irwini n. sp.</description><subject>18S rDNA</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>General aspects and techniques. Study of several systematic groups. 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M.</au><au>GILLETT, A.</au><au>RYAN, U. M.</au><au>AUSTEN, J.</au><au>CAMPBELL, R. S. F.</au><au>HANGER, J.</au><au>REID, S. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trypanosoma irwini n. sp (Sarcomastigophora: Trypanosomatidae) from the koala (Phascolarctos cinereus)</atitle><jtitle>Parasitology</jtitle><addtitle>Parasitology</addtitle><date>2009-07</date><risdate>2009</risdate><volume>136</volume><issue>8</issue><spage>875</spage><epage>885</epage><pages>875-885</pages><issn>0031-1820</issn><eissn>1469-8161</eissn><coden>PARAAE</coden><abstract>The morphology and genetic characterization of a new species of trypanosome infecting koalas (Phascolarctos cinereus) are described. Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this trypanosome species to be genetically distinct and most similar to Trypanosoma bennetti, an avian trypanosome with a genetic distance of 0·9% at the 18S rDNA and 10·7% at the gGAPDH locus. The trypanosome was detected by 18S rDNA PCR in the blood samples of 26 out of 68 (38·2%) koalas studied. The aetiological role of trypanosomes in koala disease is currently poorly defined, although infection with these parasites has been associated with severe clinical signs in a number of koalas. Based on biological and genetic characterization data, this trypanosome species infecting koalas is proposed to be a new species Trypanosome irwini n. sp.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>19570316</pmid><doi>10.1017/S0031182009006313</doi><tpages>11</tpages></addata></record> |
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| subjects | 18S rDNA Animals Biological and medical sciences Female Fundamental and applied biological sciences. Psychology General aspects General aspects and techniques. Study of several systematic groups. Models Genes, Protozoan gGAPDH Invertebrates koala Male Mammalia Parasites Phascolarctidae - parasitology Phosphoric Monoester Hydrolases - genetics Phylogeny RNA, Protozoan - analysis RNA, Ribosomal, 18S - analysis Trypanosoma - classification Trypanosoma - cytology Trypanosoma - genetics Trypanosoma spp Trypanosomiasis - parasitology Trypanosomiasis - veterinary Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution |
| title | Trypanosoma irwini n. sp (Sarcomastigophora: Trypanosomatidae) from the koala (Phascolarctos cinereus) |
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