Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects
Maternal and cord blood collected from 33 Nigerian mother–child pairs were tested for measlessepcific IgG. All 33 had protective measles antibodies at the time of delivery with a positive correlation of r = 0.87. Determination of the rate of waning of these antibodies revealed that 58 per cent of th...
Gespeichert in:
| Veröffentlicht in: | Journal of tropical pediatrics (1980) 2005-02, Vol.51 (1), p.45-48 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 48 |
|---|---|
| container_issue | 1 |
| container_start_page | 45 |
| container_title | Journal of tropical pediatrics (1980) |
| container_volume | 51 |
| creator | Oyedele, O. Oluseyi Odemuyiwa, S. O. Ammerlaan, W. Muller, C. P. Adu, F. D. |
| description | Maternal and cord blood collected from 33 Nigerian mother–child pairs were tested for measlessepcific IgG. All 33 had protective measles antibodies at the time of delivery with a positive correlation of r = 0.87. Determination of the rate of waning of these antibodies revealed that 58 per cent of these children had lost the protective maternal antibody by the age of 4 months and only 3 per cent of the children had enough antibody to protect them between the ages of 6–9 months. Fifty-five colostrum samples from the same mothers and 347 breastmilk samples collected at various periods of breastfeeding also showed that anti-measles IgA had dropped below the protective cut-off within the first 2 weeks of birth. It is evident that the Nigerian child is born with solid anti-measles antibody but the rate of waning has left a large number unprotected before the first dose of the vaccine. There is an urgent need to review the measles vaccination programme in Nigeria to protect these susceptible infants. |
| doi_str_mv | 10.1093/tropej/fmh073 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67443732</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>17831830</sourcerecordid><originalsourceid>FETCH-LOGICAL-c456t-c6ba0b74bea8d2f22f1cad1c41dca75db259fb0ff6eecf1e7736416e2b58ce513</originalsourceid><addsrcrecordid>eNqF0c1rFDEYB-Agil1bj14lCHobm-_MHu3Sbgutln5Y8RIymTc225nJmmTE_veO7NIFL57CSx7eD34IvaHkIyVzflhSXMPq0Pf3RPNnaEaFkhVXSjxHM0IFqxTn9R56lfOKEMJqIV6iPSoVoUrMZ-jrpc05_AJ81vfjEMojLhFfgM0dZBwGXO4BH6WpLn3oHrAdWryIqcVHXYwtjh5fxx7w5_ADUrADvh6bFbiSD9ALb7sMr7fvPro9Ob5ZnFbnX5Zni0_nlRNSlcqpxpJGiwZs3TLPmKfOttQJ2jqrZdswOfcN8V4BOE9Ba64EVcAaWTuQlO-jD5u-6xR_jpCL6UN20HV2gDhmo7QQXHP2X0h1zWnNyQTf_QNXcUzDdIRhTHCmp8UnVG2QSzHnBN6sU-htejSUmL-xmE0sZhPL5N9um45ND-1Ob3OYwPstsNnZzic7uJB3TinGayl2g0Mu8Pvp36aH6VSupTn99t0s5Xx5d3N1Zyj_A4gmpsM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>224327456</pqid></control><display><type>article</type><title>Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects</title><source>MEDLINE</source><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Oyedele, O. Oluseyi ; Odemuyiwa, S. O. ; Ammerlaan, W. ; Muller, C. P. ; Adu, F. D.</creator><creatorcontrib>Oyedele, O. Oluseyi ; Odemuyiwa, S. O. ; Ammerlaan, W. ; Muller, C. P. ; Adu, F. D.</creatorcontrib><description>Maternal and cord blood collected from 33 Nigerian mother–child pairs were tested for measlessepcific IgG. All 33 had protective measles antibodies at the time of delivery with a positive correlation of r = 0.87. Determination of the rate of waning of these antibodies revealed that 58 per cent of these children had lost the protective maternal antibody by the age of 4 months and only 3 per cent of the children had enough antibody to protect them between the ages of 6–9 months. Fifty-five colostrum samples from the same mothers and 347 breastmilk samples collected at various periods of breastfeeding also showed that anti-measles IgA had dropped below the protective cut-off within the first 2 weeks of birth. It is evident that the Nigerian child is born with solid anti-measles antibody but the rate of waning has left a large number unprotected before the first dose of the vaccine. There is an urgent need to review the measles vaccination programme in Nigeria to protect these susceptible infants.</description><identifier>ISSN: 0142-6338</identifier><identifier>EISSN: 1465-3664</identifier><identifier>DOI: 10.1093/tropej/fmh073</identifier><identifier>PMID: 15601649</identifier><identifier>CODEN: JTRPAO</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Antibodies, Viral - analysis ; Antibodies, Viral - immunology ; Biological and medical sciences ; Breast feeding ; Developing Countries ; Female ; Fetal Blood - immunology ; General aspects ; Human viral diseases ; Humans ; Immunity, Maternally-Acquired - immunology ; Immunity, Maternally-Acquired - physiology ; Infant ; Infant, Newborn ; Infectious diseases ; Male ; Measles - immunology ; Measles - prevention & control ; Measles virus ; Medical sciences ; Milk, Human - immunology ; Nigeria ; Pregnancy ; Prospective Studies ; Sampling Studies ; Sensitivity and Specificity ; Time Factors ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><ispartof>Journal of tropical pediatrics (1980), 2005-02, Vol.51 (1), p.45-48</ispartof><rights>2005 INIST-CNRS</rights><rights>Copyright Oxford University Press(England) Feb 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c456t-c6ba0b74bea8d2f22f1cad1c41dca75db259fb0ff6eecf1e7736416e2b58ce513</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16623854$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15601649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oyedele, O. Oluseyi</creatorcontrib><creatorcontrib>Odemuyiwa, S. O.</creatorcontrib><creatorcontrib>Ammerlaan, W.</creatorcontrib><creatorcontrib>Muller, C. P.</creatorcontrib><creatorcontrib>Adu, F. D.</creatorcontrib><title>Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects</title><title>Journal of tropical pediatrics (1980)</title><addtitle>J Trop Pediatr</addtitle><description>Maternal and cord blood collected from 33 Nigerian mother–child pairs were tested for measlessepcific IgG. All 33 had protective measles antibodies at the time of delivery with a positive correlation of r = 0.87. Determination of the rate of waning of these antibodies revealed that 58 per cent of these children had lost the protective maternal antibody by the age of 4 months and only 3 per cent of the children had enough antibody to protect them between the ages of 6–9 months. Fifty-five colostrum samples from the same mothers and 347 breastmilk samples collected at various periods of breastfeeding also showed that anti-measles IgA had dropped below the protective cut-off within the first 2 weeks of birth. It is evident that the Nigerian child is born with solid anti-measles antibody but the rate of waning has left a large number unprotected before the first dose of the vaccine. There is an urgent need to review the measles vaccination programme in Nigeria to protect these susceptible infants.</description><subject>Antibodies, Viral - analysis</subject><subject>Antibodies, Viral - immunology</subject><subject>Biological and medical sciences</subject><subject>Breast feeding</subject><subject>Developing Countries</subject><subject>Female</subject><subject>Fetal Blood - immunology</subject><subject>General aspects</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunity, Maternally-Acquired - immunology</subject><subject>Immunity, Maternally-Acquired - physiology</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Measles - immunology</subject><subject>Measles - prevention & control</subject><subject>Measles virus</subject><subject>Medical sciences</subject><subject>Milk, Human - immunology</subject><subject>Nigeria</subject><subject>Pregnancy</subject><subject>Prospective Studies</subject><subject>Sampling Studies</subject><subject>Sensitivity and Specificity</subject><subject>Time Factors</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><issn>0142-6338</issn><issn>1465-3664</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c1rFDEYB-Agil1bj14lCHobm-_MHu3Sbgutln5Y8RIymTc225nJmmTE_veO7NIFL57CSx7eD34IvaHkIyVzflhSXMPq0Pf3RPNnaEaFkhVXSjxHM0IFqxTn9R56lfOKEMJqIV6iPSoVoUrMZ-jrpc05_AJ81vfjEMojLhFfgM0dZBwGXO4BH6WpLn3oHrAdWryIqcVHXYwtjh5fxx7w5_ADUrADvh6bFbiSD9ALb7sMr7fvPro9Ob5ZnFbnX5Zni0_nlRNSlcqpxpJGiwZs3TLPmKfOttQJ2jqrZdswOfcN8V4BOE9Ba64EVcAaWTuQlO-jD5u-6xR_jpCL6UN20HV2gDhmo7QQXHP2X0h1zWnNyQTf_QNXcUzDdIRhTHCmp8UnVG2QSzHnBN6sU-htejSUmL-xmE0sZhPL5N9um45ND-1Ob3OYwPstsNnZzic7uJB3TinGayl2g0Mu8Pvp36aH6VSupTn99t0s5Xx5d3N1Zyj_A4gmpsM</recordid><startdate>20050201</startdate><enddate>20050201</enddate><creator>Oyedele, O. Oluseyi</creator><creator>Odemuyiwa, S. O.</creator><creator>Ammerlaan, W.</creator><creator>Muller, C. P.</creator><creator>Adu, F. D.</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T5</scope><scope>7TM</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>20050201</creationdate><title>Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects</title><author>Oyedele, O. Oluseyi ; Odemuyiwa, S. O. ; Ammerlaan, W. ; Muller, C. P. ; Adu, F. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456t-c6ba0b74bea8d2f22f1cad1c41dca75db259fb0ff6eecf1e7736416e2b58ce513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Antibodies, Viral - analysis</topic><topic>Antibodies, Viral - immunology</topic><topic>Biological and medical sciences</topic><topic>Breast feeding</topic><topic>Developing Countries</topic><topic>Female</topic><topic>Fetal Blood - immunology</topic><topic>General aspects</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunity, Maternally-Acquired - immunology</topic><topic>Immunity, Maternally-Acquired - physiology</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Measles - immunology</topic><topic>Measles - prevention & control</topic><topic>Measles virus</topic><topic>Medical sciences</topic><topic>Milk, Human - immunology</topic><topic>Nigeria</topic><topic>Pregnancy</topic><topic>Prospective Studies</topic><topic>Sampling Studies</topic><topic>Sensitivity and Specificity</topic><topic>Time Factors</topic><topic>Viral diseases</topic><topic>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oyedele, O. Oluseyi</creatorcontrib><creatorcontrib>Odemuyiwa, S. O.</creatorcontrib><creatorcontrib>Ammerlaan, W.</creatorcontrib><creatorcontrib>Muller, C. P.</creatorcontrib><creatorcontrib>Adu, F. D.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of tropical pediatrics (1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oyedele, O. Oluseyi</au><au>Odemuyiwa, S. O.</au><au>Ammerlaan, W.</au><au>Muller, C. P.</au><au>Adu, F. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects</atitle><jtitle>Journal of tropical pediatrics (1980)</jtitle><addtitle>J Trop Pediatr</addtitle><date>2005-02-01</date><risdate>2005</risdate><volume>51</volume><issue>1</issue><spage>45</spage><epage>48</epage><pages>45-48</pages><issn>0142-6338</issn><eissn>1465-3664</eissn><coden>JTRPAO</coden><abstract>Maternal and cord blood collected from 33 Nigerian mother–child pairs were tested for measlessepcific IgG. All 33 had protective measles antibodies at the time of delivery with a positive correlation of r = 0.87. Determination of the rate of waning of these antibodies revealed that 58 per cent of these children had lost the protective maternal antibody by the age of 4 months and only 3 per cent of the children had enough antibody to protect them between the ages of 6–9 months. Fifty-five colostrum samples from the same mothers and 347 breastmilk samples collected at various periods of breastfeeding also showed that anti-measles IgA had dropped below the protective cut-off within the first 2 weeks of birth. It is evident that the Nigerian child is born with solid anti-measles antibody but the rate of waning has left a large number unprotected before the first dose of the vaccine. There is an urgent need to review the measles vaccination programme in Nigeria to protect these susceptible infants.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>15601649</pmid><doi>10.1093/tropej/fmh073</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0142-6338 |
| ispartof | Journal of tropical pediatrics (1980), 2005-02, Vol.51 (1), p.45-48 |
| issn | 0142-6338 1465-3664 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67443732 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Antibodies, Viral - analysis Antibodies, Viral - immunology Biological and medical sciences Breast feeding Developing Countries Female Fetal Blood - immunology General aspects Human viral diseases Humans Immunity, Maternally-Acquired - immunology Immunity, Maternally-Acquired - physiology Infant Infant, Newborn Infectious diseases Male Measles - immunology Measles - prevention & control Measles virus Medical sciences Milk, Human - immunology Nigeria Pregnancy Prospective Studies Sampling Studies Sensitivity and Specificity Time Factors Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye |
| title | Passive Immunity to Measles in the Breastmilk and Cord Blood of Some Nigerian Subjects |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T01%3A20%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Passive%20Immunity%20to%20Measles%20in%20the%20Breastmilk%20and%20Cord%20Blood%20of%20Some%20Nigerian%20Subjects&rft.jtitle=Journal%20of%20tropical%20pediatrics%20(1980)&rft.au=Oyedele,%20O.%20Oluseyi&rft.date=2005-02-01&rft.volume=51&rft.issue=1&rft.spage=45&rft.epage=48&rft.pages=45-48&rft.issn=0142-6338&rft.eissn=1465-3664&rft.coden=JTRPAO&rft_id=info:doi/10.1093/tropej/fmh073&rft_dat=%3Cproquest_cross%3E17831830%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=224327456&rft_id=info:pmid/15601649&rfr_iscdi=true |