Potential application of the ATP cell viability assay in the measurement of intrinsic radiosensitivity in cervical cancer

Intrinsic radiosensitivity using the clonogenic assay and the cell surviving fraction at 2 Gy (SF 2) has been shown to be an independent prognostic factor for patient response to radiotherapy in carcinoma of the cervix. The clonogenic assay has significant shortcomings, making it unsuitable for rout...

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Veröffentlicht in:	Gynecologic oncology 2005-03, Vol.96 (3), p.765-770
Hauptverfasser:	Tam, K.F., Ng, T.Y., Liu, S.S., Tsang, P.C.K., Kwong, P.W.K., Ngan, H.Y.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism ATP cell viability assay Cell Line, Tumor Cell Survival - radiation effects Cervical cancer Female HeLa Cells Humans Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - radiation effects Radiation Tolerance Radiosensitivity Tumor Stem Cell Assay - methods Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - radiotherapy
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