Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats

In the present study, we tested the ability of sevoflurane to induce early and late preconditioning against ischemic neuronal injury using an in vivo model of global cerebral ischemia in the rat. Seven-minute global ischemia was induced by cardiac arrest, followed by resuscitation and recovery for 7...

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Veröffentlicht in:	Brain research 2005-02, Vol.1034 (1), p.147-152
Hauptverfasser:	Payne, Ralphiel S., Akca, Ozan, Roewer, Norbert, Schurr, Avital, Kehl, Franz
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - physiology Anesthetics, Inhalation - pharmacology Animals Biological and medical sciences Brain Ischemia - drug therapy Brain Ischemia - pathology Brain Ischemia - physiopathology Cell Death - drug effects Cell Death - physiology Cerebral ischemia Disease Models, Animal Heart Arrest, Induced Hippocampal neuronal injury Hippocampus - drug effects Hippocampus - pathology Hippocampus - physiopathology Male Medical sciences Methyl Ethers - pharmacology Nerve Degeneration - pathology Nerve Degeneration - physiopathology Nerve Degeneration - prevention & control Neurons - drug effects Neurons - pathology Neurons - physiology Neuropharmacology Neuroprotective agent Neuroprotective Agents - pharmacology Organ Culture Techniques Pharmacology. Drug treatments Preconditioning Rats Rats, Sprague-Dawley Reperfusion Injury - pathology Reperfusion Injury - physiopathology Reperfusion Injury - prevention & control Treatment Outcome Volatile Anesthetics
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