Quality of life in patients with pituitary tumors
Quality of life (QoL) is impaired in patients with pituitary tumors, even after biochemical cure. However, it is not usually assessed in daily practice. The aim of this study is to highlight recent findings on QoL in the different types of pituitary adenomas and hypopituitarism. Patients with acrome...
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| Veröffentlicht in: | Current opinion in endocrinology, diabetes, and obesity diabetes, and obesity, 2009-08, Vol.16 (4), p.299-303 |
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| container_title | Current opinion in endocrinology, diabetes, and obesity |
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| creator | Santos, Alicia Resmini, Eugenia Martínez, María-Antonia Martí, Camelia Ybarra, Juan Webb, Susan M |
| description | Quality of life (QoL) is impaired in patients with pituitary tumors, even after biochemical cure. However, it is not usually assessed in daily practice. The aim of this study is to highlight recent findings on QoL in the different types of pituitary adenomas and hypopituitarism.
Patients with acromegaly or Cushing's syndrome have the greatest impairment of QoL, and concomitant hypopituitarism worsens it further. The use of disease-generated QoL questionnaires allows dimensions specifically affected in that disease to be addressed and these dimensions are more sensitive to change after successful therapy; in some cases, improvement in patients' sense of well-being has been shown despite no hormonal change, indicating that evaluation of QoL is not such a soft end-point as thought by some.
Systematic evaluation of QoL in patients with pituitary diseases provides information not always contemplated by hormonal and routine clinical evaluation; this allows detection of not often contemplated health problems, which may then be approached and treated, improving the care provided to these patients. |
| doi_str_mv | 10.1097/MED.0b013e32832cdec9 |
| format | Article |
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Patients with acromegaly or Cushing's syndrome have the greatest impairment of QoL, and concomitant hypopituitarism worsens it further. The use of disease-generated QoL questionnaires allows dimensions specifically affected in that disease to be addressed and these dimensions are more sensitive to change after successful therapy; in some cases, improvement in patients' sense of well-being has been shown despite no hormonal change, indicating that evaluation of QoL is not such a soft end-point as thought by some.
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Patients with acromegaly or Cushing's syndrome have the greatest impairment of QoL, and concomitant hypopituitarism worsens it further. The use of disease-generated QoL questionnaires allows dimensions specifically affected in that disease to be addressed and these dimensions are more sensitive to change after successful therapy; in some cases, improvement in patients' sense of well-being has been shown despite no hormonal change, indicating that evaluation of QoL is not such a soft end-point as thought by some.
Systematic evaluation of QoL in patients with pituitary diseases provides information not always contemplated by hormonal and routine clinical evaluation; this allows detection of not often contemplated health problems, which may then be approached and treated, improving the care provided to these patients.</description><subject>Acromegaly - psychology</subject><subject>Cushing Syndrome - psychology</subject><subject>Humans</subject><subject>Hypopituitarism - psychology</subject><subject>Pituitary Neoplasms - psychology</subject><subject>Quality of Life</subject><issn>1752-296X</issn><issn>1752-2978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE1LAzEQhoMotlb_gcievG2dJJtscpRaP6AigoK3kM0mNLrbrUmW0n_vqsWCh2Hm8L4Pw4PQOYYpBllePc5vplABppYSQYmprZEHaIxLRnIiS3H4d_O3ETqJ8R2AlSVjx2iEZSEx52KM8HOvG5-2Weeyxjub-VW21snbVYrZxqdltvap90mHbZb6tgvxFB053UR7ttsT9Ho7f5nd54unu4fZ9SI3lAHLayIc19Q5S2rrpMUFpYZVAmtwgJmpTCVoMXwuiSl4pTWunaiFdAZDXQpBJ-jyl7sO3WdvY1Ktj8Y2jV7Zro-KlwOR_wSL36AJXYzBOrUOvh0eVhjUtyo1qFL_VQ21ix2_r1pb70s7N3vupmuSDfGj6Tc2qKXVTVoqwIRzIDInABIEAOTDAKNf5GZ2JA</recordid><startdate>20090801</startdate><enddate>20090801</enddate><creator>Santos, Alicia</creator><creator>Resmini, Eugenia</creator><creator>Martínez, María-Antonia</creator><creator>Martí, Camelia</creator><creator>Ybarra, Juan</creator><creator>Webb, Susan M</creator><general>Wolters Kluwer Health, Inc. All rights reserved</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090801</creationdate><title>Quality of life in patients with pituitary tumors</title><author>Santos, Alicia ; Resmini, Eugenia ; Martínez, María-Antonia ; Martí, Camelia ; Ybarra, Juan ; Webb, Susan M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3505-d28f6a3ffe2def9e1433c5b81a0f015cbcb83428392c46baa1df8d89fc10d7883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Acromegaly - psychology</topic><topic>Cushing Syndrome - psychology</topic><topic>Humans</topic><topic>Hypopituitarism - psychology</topic><topic>Pituitary Neoplasms - psychology</topic><topic>Quality of Life</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Santos, Alicia</creatorcontrib><creatorcontrib>Resmini, Eugenia</creatorcontrib><creatorcontrib>Martínez, María-Antonia</creatorcontrib><creatorcontrib>Martí, Camelia</creatorcontrib><creatorcontrib>Ybarra, Juan</creatorcontrib><creatorcontrib>Webb, Susan M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in endocrinology, diabetes, and obesity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Santos, Alicia</au><au>Resmini, Eugenia</au><au>Martínez, María-Antonia</au><au>Martí, Camelia</au><au>Ybarra, Juan</au><au>Webb, Susan M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality of life in patients with pituitary tumors</atitle><jtitle>Current opinion in endocrinology, diabetes, and obesity</jtitle><addtitle>Curr Opin Endocrinol Diabetes Obes</addtitle><date>2009-08-01</date><risdate>2009</risdate><volume>16</volume><issue>4</issue><spage>299</spage><epage>303</epage><pages>299-303</pages><issn>1752-296X</issn><eissn>1752-2978</eissn><abstract>Quality of life (QoL) is impaired in patients with pituitary tumors, even after biochemical cure. However, it is not usually assessed in daily practice. The aim of this study is to highlight recent findings on QoL in the different types of pituitary adenomas and hypopituitarism.
Patients with acromegaly or Cushing's syndrome have the greatest impairment of QoL, and concomitant hypopituitarism worsens it further. The use of disease-generated QoL questionnaires allows dimensions specifically affected in that disease to be addressed and these dimensions are more sensitive to change after successful therapy; in some cases, improvement in patients' sense of well-being has been shown despite no hormonal change, indicating that evaluation of QoL is not such a soft end-point as thought by some.
Systematic evaluation of QoL in patients with pituitary diseases provides information not always contemplated by hormonal and routine clinical evaluation; this allows detection of not often contemplated health problems, which may then be approached and treated, improving the care provided to these patients.</abstract><cop>England</cop><pub>Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>19491668</pmid><doi>10.1097/MED.0b013e32832cdec9</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 1752-296X |
| ispartof | Current opinion in endocrinology, diabetes, and obesity, 2009-08, Vol.16 (4), p.299-303 |
| issn | 1752-296X 1752-2978 |
| language | eng |
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| source | Journals@Ovid Ovid Autoload; MEDLINE |
| subjects | Acromegaly - psychology Cushing Syndrome - psychology Humans Hypopituitarism - psychology Pituitary Neoplasms - psychology Quality of Life |
| title | Quality of life in patients with pituitary tumors |
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