Ubiquitous mitochondrial creatine kinase is overexpressed in the conditioned medium and the extract of LNCaP lineaged androgen independent cell lines and facilitates prostate cancer progression

BACKGROUND Androgen independent prostate cancer (AIPC) is not responsive to androgen ablation therapy. The biomarkers of AIPC are lack. Numerous proteomics studies have focused on finding new markers of AIPC and exploring their possible functions, but little is known about the difference between con...

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Veröffentlicht in:	The Prostate 2009-08, Vol.69 (11), p.1176-1187
Hauptverfasser:	Pang, Bo, Zhang, Hui, Wang, Jian, Chen, Wen-Zheng, Li, Shan-Hu, Shi, Qing-Guo, Liang, Rei-Xia, Xie, Bang-Xiang, Wu, Rui-Qin, Qian, Xiao-Long, Yu, Lan, Li, Qi-Man, Huang, Cui-Fen, Zhou, Jian-Guang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Amino Acid Sequence androgen independent Androgens - metabolism Biological and medical sciences Biomarkers, Tumor - metabolism Cell Line, Tumor Cell Proliferation Creatine Kinase, Mitochondrial Form - analysis Creatine Kinase, Mitochondrial Form - metabolism Culture Media, Conditioned - metabolism Disease Progression Gynecology. Andrology. Obstetrics Humans Insulin-Like Growth Factor Binding Protein 2 - metabolism Male Male genital diseases Medical sciences Molecular Sequence Data Nephrology. Urinary tract diseases prostate cancer Prostate-Specific Antigen - metabolism Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology proteomics Proto-Oncogene Proteins c-akt - metabolism reactive oxygen species Reactive Oxygen Species - metabolism Tumors Tumors of the urinary system ubiquitous mitochondrial creatine kinase Urinary tract. Prostate gland
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