Novel cationic pentablock copolymers as non-viral vectors for gene therapy

New cationic pentablock copolymers of poly(diethylaminoethylmethacrylate) (PDEAEM), poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO)—PDEAEM-b-PEO-b-PPO-b-PEO-b-PDEAEM—synthesized in our laboratory were investigated for their potential as non-viral vectors for gene therapy. Agarose gel stud...

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Veröffentlicht in:	Journal of controlled release 2005-03, Vol.103 (1), p.245-258
Hauptverfasser:	Agarwal, Ankit, Unfer, Robert, Mallapragada, Surya K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Block copolymers Cationic Cations Cell Line, Tumor Gene therapy General pharmacology Genetic Therapy - methods Genetic Vectors - administration & dosage Genetic Vectors - genetics Humans Injectable Medical sciences Non-viral vectors pH sensitive Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers - administration & dosage
Online-Zugang:	Volltext
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