Coexpression of Erythropoietin and Erythropoietin Receptor in Von Hippel-Lindau Disease–Associated Renal Cysts and Renal Cell Carcinoma

Von Hippel-Lindau (VHL) disease is characterized by multiple tumors in specific target organs. The tumors at different sites share distinct morphologic and genetic characteristics but their cell of origin is unknown. We show that VHL disease–associated renal clear cell carcinomas (RCC) consistently...

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Veröffentlicht in:	Clinical cancer research 2005-02, Vol.11 (3), p.1059-1064
Hauptverfasser:	LEE, Youn-Soo, VORTMEYER, Alexander O, TEH, Bin T, RICHARD, Stéphane, ZHENGPING ZHUANG, LUBENSKY, Irina A, VOGEL, Timothy W. A, IKEJIRI, Barbara, FERLICOT, Sophie, BENOIT, Gérard, GIRAUD, Sophie, OLDFIELD, Edward H, LINEHAN, W. Marston
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Blotting, Western Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Epo EpoR Erythropoietin - genetics Erythropoietin - metabolism Female Gene Expression Humans Immunohistochemistry Kidney Diseases, Cystic - genetics Kidney Diseases, Cystic - metabolism Kidney Diseases, Cystic - pathology Kidney Neoplasms - genetics Kidney Neoplasms - pathology Kidneys Male Medical sciences Nephrology. Urinary tract diseases Pharmacology. Drug treatments Receptors, Erythropoietin - genetics Receptors, Erythropoietin - metabolism renal cell carcinoma renal cyst Reverse Transcriptase Polymerase Chain Reaction RNA, Neoplasm - genetics RNA, Neoplasm - metabolism RT-PCR Tumors of the urinary system Von Hippel-Lindau disease von Hippel-Lindau Disease - complications Western blot
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