Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease

Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme regulating the metabolism of folate and methionine. The potential influence of MTHFR activity on DNA methylation and on the availability of uridylates and thymidylates for DNA synthesis and repair presents MTHFR as a candidate for bein...

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Veröffentlicht in:	Human genetics 2005-03, Vol.116 (4), p.247-254
Hauptverfasser:	ZOODSMA, Margreet, NOLTE, Ilja M, SCHIPPER, Martin, OOSTEROM, Elvira, VAN DER STEEGE, Gerrit, DE VRIES, Elisabeth G. E, TE MEERMAN, Gerard J, VAN DER ZEE, Ate G. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Case-Control Studies Cervical cancer Classical genetics, quantitative genetics, hybrids DNA methylation DNA Primers Enzymes Female Fundamental and applied biological sciences. Psychology Genes Genetic Predisposition to Disease Genetics of eukaryotes. Biological and molecular evolution Human Human papillomavirus Humans Metabolism Methylenetetrahydrofolate Reductase (NADPH2) - genetics Polymorphism Precancerous Conditions - genetics Uterine Cervical Neoplasms - genetics Vitamin B
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