Novel role of prostate-specific membrane antigen in suppressing prostate cancer invasiveness

Prostate-specific membrane antigen (PSMA), a type II transmembrane glycoprotein, is overexpressed in prostate cancer. PSMA is a unique cell surface marker, negatively regulated by androgen and extensively used for imaging of hormone refractory carcinomas and metastatic foci. PSMA is a carboxypeptida...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2005-02, Vol.65 (3), p.727-731
Hauptverfasser:	GHOSH, Arundhati, XINNING WANG, KLEIN, Eric, HESTON, Warren D. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Surface - biosynthesis Antigens, Surface - physiology Antineoplastic agents Biological and medical sciences Cell Line, Tumor Glutamate Carboxypeptidase II - biosynthesis Glutamate Carboxypeptidase II - deficiency Glutamate Carboxypeptidase II - physiology Humans Male Medical sciences Neoplasm Invasiveness Pharmacology. Drug treatments Prostatic Neoplasms - enzymology Prostatic Neoplasms - immunology Prostatic Neoplasms - pathology
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