Determination of main low molecular weight antioxidants in urinary bladder wall using HPLC with electrochemical detector

The aim of the present work was to develop validated HPLC method using electrochemical detector for simultaneous detection of low molecular weight antioxidants (LMWA) in urinary bladder. Furthermore, the method was applied to study the distribution of LMWA in urinary bladder wall. The ascorbic acid...

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Veröffentlicht in:	International journal of pharmaceutics 2005-03, Vol.291 (1), p.161-169
Hauptverfasser:	Vovk, T., Bogataj, M., Roškar, R., Kmetec, V., Mrhar, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - analysis Antioxidants - metabolism Ascorbic Acid - analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Electrochemical detector Electrochemistry - instrumentation Electrochemistry - methods General pharmacology Glutathione - analysis Glutathione Disulfide - analysis HPLC Low molecular weight antioxidants Medical sciences Molecular Weight Muscle, Smooth - chemistry Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Phosphoric Acids - analysis Serous Membrane - chemistry Swine Technology, Pharmaceutical - methods Technology, Pharmaceutical - trends Tissue Extracts - analysis Tissue Extracts - chemistry Uric Acid - analysis Urinary Bladder - chemistry Urinary Bladder - metabolism Urinary bladder wall Urothelium - chemistry
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