Localization, anchoring and translational control of oskar, gurken, bicoid and nanos mRNA during Drosophila oogenesis

mRNA localization, and translation that is regulated spatially and temporally, are key mechanisms in the execution of polarized developmental programs. For over two decades, the Drosophila oocyte has served as a valuable model to study these mechanisms. Genetic and biochemical studies in flies have...

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Veröffentlicht in:	Fly (Austin, Tex.) Tex.), 2009-01, Vol.3 (1), p.15-28
Hauptverfasser:	Kugler, Jan-Michael, Lasko, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Biological Transport, Active Biology Bioscience Calcium Cancer Cell Cell Polarity Cycle Drosophila - genetics Drosophila - growth & development Drosophila - metabolism Drosophila Proteins - biosynthesis Drosophila Proteins - genetics Female Genes, Insect Homeodomain Proteins - biosynthesis Homeodomain Proteins - genetics Landes Microtubules - metabolism Models, Biological Oogenesis - genetics Organogenesis Protein Biosynthesis Proteins RNA, Messenger - genetics RNA, Messenger - metabolism RNA-Binding Proteins - biosynthesis RNA-Binding Proteins - genetics Trans-Activators - biosynthesis Trans-Activators - genetics Transforming Growth Factor alpha - biosynthesis Transforming Growth Factor alpha - genetics
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