A Combined-Formulation Tablet of Lamivudine/Nevirapine/Stavudine: Bioequivalence Compared With Concurrent Administration of Lamivudine, Nevirapine, and Stavudine in Healthy Indian Subjects

Generic fixed‐dose combinations of antiretrovirals are frequently prescribed for the treatment of human immunodeficiency virus infection. A randomized, 2‐way study was conducted in 24 fasting, healthy, Indian male subjects to assess bioequivalence between a single combination tablet containing lamiv...

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Veröffentlicht in:	Journal of clinical pharmacology 2005-03, Vol.45 (3), p.265-274
Hauptverfasser:	Narang, Vishal S., Lulla, Amar, Malhotra, Geena, Purandare, Shrinivas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - blood Anti-HIV Agents - pharmacokinetics bioequivalence Complications and side effects Cross-Over Studies Dosage and administration Drug Combinations Drug therapy Drug Therapy, Combination HIV infection Human immunodeficiency virus Humans India Lamivudine Lamivudine - administration & dosage Lamivudine - blood Lamivudine - pharmacokinetics Male Nevirapine Nevirapine - administration & dosage Nevirapine - blood Nevirapine - pharmacokinetics Pharmacokinetics Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - blood Reverse Transcriptase Inhibitors - pharmacokinetics Stavudine Stavudine - administration & dosage Stavudine - blood Stavudine - pharmacokinetics Tablets Therapeutic Equivalency
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