Limits of multi-linear gradient optimisation in reversed-phase liquid chromatography

The concept of limiting peak purity was applied to quantify the degree of completion of the separation capability of a chromatographic system using multi-linear gradients. The objective was to check whether the complexity of a gradient program deserves be increased to enhance resolution by inserting...

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Veröffentlicht in:	Journal of Chromatography A 2005-01, Vol.1063 (1), p.79-88
Hauptverfasser:	Concha-Herrera, V., Vivó-Truyols, G., Torres-Lapasió, J.R., García-Alvarez-Coque, M.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, Liquid - methods Exact sciences and technology Gradient elution Limiting resolution Multi-linear gradients Other chromatographic methods Peak purity
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