Hyperhomocysteinaemia in chronic liver diseases: role of disease stage, vitamin status and methylenetetrahydrofolate reductase genetics

: Background/Aims: The liver plays a key role in sulphur aminoacid metabolism hence, homocysteine metabolism may be impaired in chronic liver diseases. The aim of this study was to investigate, in patients affected by chronic liver diseases, (1) the prevalence of hyperhomocysteinaemia and (2) the ro...

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Veröffentlicht in:	Liver international 2005-02, Vol.25 (1), p.49-56
Hauptverfasser:	Ventura, Paolo, Rosa, Maria Cristina, Abbati, Gianluca, Marchini, Stefano, Grandone, Elvira, Vergura, Patrizia, Tremosini, Silvia, Zeneroli, Maria Luisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Avitaminosis Carcinoma, Hepatocellular - complications Carcinoma, Hepatocellular - enzymology Carcinoma, Hepatocellular - pathology chronic active hepatitis Chronic Disease fatty liver Fatty Liver - complications Fatty Liver - enzymology Fatty Liver - pathology Genetic Predisposition to Disease Hepatitis, Chronic - complications Hepatitis, Chronic - enzymology Hepatitis, Chronic - pathology Humans hyperhomocysteinaemia Hyperhomocysteinemia - complications Hyperhomocysteinemia - enzymology Hyperhomocysteinemia - pathology liver cirrhosis Liver Cirrhosis - complications Liver Cirrhosis - enzymology Liver Cirrhosis - pathology Liver Diseases - complications Liver Diseases - enzymology Liver Diseases - pathology Liver Neoplasms - complications Liver Neoplasms - enzymology Liver Neoplasms - pathology Methylenetetrahydrofolate Reductase (NADPH2) - genetics MTHFR Mutation, Missense Point Mutation
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