Functional characteristics of apheresis-derived platelets treated with ultraviolet light combined with either amotosalen-HCl (S-59) or riboflavin (vitamin B2) for pathogen-reduction

Background To examine if different pathogen‐reduction technologies (PRTs) induce different degrees of platelet (PLT) storage lesion. Design Twenty‐seven split triple‐dose apheresis PLTs were PRT treated using ultraviolet light with either riboflavin (M) or psoralen (I) or remained untreated (C). S...

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Veröffentlicht in:	Vox sanguinis 2009-07, Vol.97 (1), p.26-33
Hauptverfasser:	Picker, S. M., Oustianskaia, L., Schneider, V., Gathof, B. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood & organ donations Blood Platelets - cytology Blood Platelets - metabolism Blood Preservation Blood products Comparative studies Disinfection - methods Furocoumarins - pharmacology Humans in vitro cell quality INTERCEPT BLOOD SYSTEM MIRASOL-PRT pathogen-reduction technology Photosensitizing Agents - pharmacology Placental Function Tests - methods Platelet Aggregation - drug effects Platelet Aggregation - radiation effects Platelet Count platelet storage lesion Plateletpheresis - methods Riboflavin - pharmacology Storage Ultraviolet radiation Ultraviolet Rays
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