Notch signaling enhances osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells

Objective The Notch signaling pathway has been shown to play a role in bone marrow−derived stromal cell differentiation, however, the precise outcome of Notch activation remains controversial. The aim of this study was to evaluate the effect of Notch signaling in primary human bone marrow−derived st...

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Veröffentlicht in:Experimental hematology 2009-07, Vol.37 (7), p.867-875.e1
Hauptverfasser: Ugarte, Fernando, Ryser, Martin, Thieme, Sebastian, Fierro, Fernando A, Navratiel, Katrin, Bornhäuser, Martin, Brenner, Sebastian
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Sprache:eng
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