Laser Doppler Imaging of Reactive Hyperemia Exposes Blood Flow Deficits in a Rat Model of Experimental Limb Ischemia

The primary pathophysiology of peripheral artery occlusive disease is associated with impaired perfusion to the lower extremities. The lack of effective pharmacologic agents to treat this disease emphasizes the need for well-characterized animal models that can be used to evaluate the efficacy of em...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2009-06, Vol.53 (6), p.446-451
Hauptverfasser:	Corcoran, Halea A, Smith, Brad E, Mathers, Parker, Pisacreta, Dan, Hershey, James C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Collateral Circulation Disease Models, Animal Hindlimb - blood supply Hyperemia - physiopathology Ischemia - physiopathology Laser-Doppler Flowmetry Male Microcirculation Muscle, Skeletal - blood supply Rats Rats, Sprague-Dawley Regional Blood Flow
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