Control of human host immunity to mycobacteria

Infection with Mycobacterium tuberculosis results in disease in 5–10% of exposed individuals, whereas the remainder controls infection effectively. Similar inter-individual differences in disease susceptibility are characteristic features of leprosy, typhoid fever, leishmaniasis and other chronic in...

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Veröffentlicht in:	Tuberculosis (Edinburgh, Scotland) Scotland), 2005-01, Vol.85 (1), p.53-64
Hauptverfasser:	Ottenhoff, Tom H.M., Verreck, Frank A.W., Hoeve, Marieke A., Vosse, Esther van de
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - genetics Cytokines - genetics Cytokines - immunology Genetic Predisposition to Disease - genetics Genetic susceptibility Humans IFN- γ (receptor) IL-12 (receptor) IL-23 (receptor) Immunity, Cellular - genetics Immunity, Cellular - immunology Interferon-gamma - genetics Interferon-gamma - immunology Interleukin-12 - genetics Interleukin-12 - immunology Interleukin-23 Interleukin-23 Subunit p19 Interleukins - genetics Interleukins - immunology Mycobacterium Infections - genetics Mycobacterium Infections - immunology Receptors, Interferon - genetics Receptors, Interferon - immunology Receptors, Interleukin - genetics Receptors, Interleukin - immunology Salmonella Infections - genetics Salmonella Infections - immunology Signal Transduction - genetics Signal Transduction - immunology Tuberculosis Tuberculosis - genetics Tuberculosis - immunology
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