Haplotype-based analysis of alpha 2A, 2B, and 2C adrenergic receptor genes captures information on common functional loci at each gene

The alpha 2-adrenergic receptors (alpha2-AR) mediate physiological effects of epinephrine and norepinephrine. Three genes encode alpha2-AR subtypes carrying common functional polymorphisms (ADRA2A Asn251Lys, ADRA2B Ins/Del301-303 and ADRA2C Ins/Del322-325). We genotyped these functional markers plus...

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Veröffentlicht in:	Journal of human genetics 2005-01, Vol.50 (1), p.12-20
Hauptverfasser:	Belfer, Inna, Buzas, Beata, Hipp, Heather, Phillips, Gabriel, Taubman, Julie, Lorincz, Ilona, Evans, Catherine, Lipsky, Robert H, Enoch, Mary-Anne, Max, Mitchell B, Goldman, David
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - genetics Base Sequence Chromosome Mapping Chromosomes, Human, Pair 10 - genetics Chromosomes, Human, Pair 2 - genetics Chromosomes, Human, Pair 4 - genetics DNA - genetics European Continental Ancestry Group - genetics Genetic Markers Genetic Variation Haplotypes Humans Linkage Disequilibrium Polymorphism, Single Nucleotide Receptors, Adrenergic, alpha-2 - classification Receptors, Adrenergic, alpha-2 - genetics
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