Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8

The plant sterol diosgenin has been shown to stimulate biliary cholesterol secretion in mice without affecting the expression of the adenosine triphosphate-binding cassette transporter heterodimer Abcg5/g8. The aim of this study was to investigate the mechanism of diosgenin-induced cholesterol hyper...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2005, Vol.41 (1), p.141-150
Hauptverfasser:	KOSTERS, Astrid, FRIJTERS, Raoul J. J. M, KUNNE, Cindy, VINK, Edwin, SCHNEIDERS, Marit S, SCHAAP, Frank G, NIBBERING, Catherina P, FATEL, Shailendra B, GROEN, Albert K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter, Sub-Family G, Member 5 ATP Binding Cassette Transporter, Sub-Family G, Member 8 ATP-Binding Cassette Transporters - metabolism Biliary Tract - drug effects Biliary Tract - secretion Biological and medical sciences Cholesterol - secretion Delivery. Postpartum. Lactation Diosgenin - pharmacology Female Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gynecology. Andrology. Obstetrics Kinetics Lipoproteins - metabolism Liver. Bile. Biliary tracts Male Medical sciences Mice Mice, Inbred Strains Mice, Knockout Vertebrates: digestive system
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