Effects of Chronic Administration of Fruit Extract (Citrus unshiu MARC) on Endothelial Dysfunction in Streptozotocin-Induced Diabetic Rats

We investigated the effects of chronic administration of fruit extract (Citrus unshiu MARC) on the endothelial dysfunction seen in aortae from streptozotocin (STZ)-induced diabetic rats. A ten-week administration of this fruit extract preserved acetylcholine (ACh)-induced endothelium-dependent relax...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2005, Vol.28(2), pp.267-270
Hauptverfasser:	Kamata, Katsuo, Kobayashi, Tsuneo, Matsumoto, Takayuki, Kanie, Noriyasu, Oda, Shu-ichi, Kaneda, Akihito, Sugiura, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Animals aorta Aorta, Thoracic - drug effects Aorta, Thoracic - physiology Citrus Citrus unshiu diabetes Diabetes Mellitus, Experimental - diet therapy Diabetes Mellitus, Experimental - pathology Dose-Response Relationship, Drug endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - pathology Endothelium, Vascular - physiology Male Plant Extracts - administration & dosage Rats Rats, Wistar relaxation Vasodilation - drug effects Vasodilation - physiology
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