Comparative Proteomic Analysis of Antibiotic-Sensitive and Insensitive Isolates of Orientia tsutsugamushi

Scrub typhus, caused by infection with Orientia tsutsugamushi, is probably the most common severe rickettsial disease. Early diagnosis followed by treatment with antibiotics such as doxycycline or chloramphenicol usually quickly decreases fever in patients, and they often recover well from other sym...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2009-05, Vol.1166 (1), p.27-37
Hauptverfasser:	Chao, Chien-Chung, Garland, Donita L., Dasch, Gregory A., Ching, Wei-Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use antibiotic sensitive Bacterial Proteins - analysis Bacterial Proteins - genetics Bacterial Typing Techniques Chromatography, Liquid Doxycycline - therapeutic use Drug Resistance, Bacterial - physiology Electrophoresis, Gel, Two-Dimensional Humans Mass Spectrometry Orientia tsutsugamushi Orientia tsutsugamushi - drug effects Orientia tsutsugamushi - metabolism Proteome - analysis Proteomic Proteomics - methods Scrub Typhus - drug therapy Scrub Typhus - etiology Scrub Typhus - microbiology
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