Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists

The disruption of prepulse inhibition (PPI) in rats by dopamine (DA) agonists is used to study the neural basis of strain differences in dopaminergic function. We reported that, compared to Long–Evans (LEH) rats, Sprague–Dawley (SDH) rats are more sensitive to the PPI-disruptive effects of the direc...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2005-02, Vol.80 (2), p.203-211
Hauptverfasser:	Swerdlow, Neal R., Kuczenski, Ronald, Goins, Jana C., Crain, Sarah K., Ma, Lillian T., Bongiovanni, Michele J., Shoemaker, Jody M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Amphetamine Animals Apomorphine Behavioral psychophysiology Biological and medical sciences Brain - drug effects Brain - metabolism Dopamine Dopamine - genetics Dopamine - metabolism Dopamine Agonists - pharmacology Female Fundamental and applied biological sciences. Psychology Male Medial prefrontal cortex Neurotransmission and behavior Nucleus accumbens Prepulse inhibition Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Long-Evans Rats, Sprague-Dawley Reflex, Startle - drug effects Reflex, Startle - genetics Reflexes Schizophrenia Species Specificity Startle Striatum
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