Role of natural killer T (NKT) cells lacking interleukin (IL)-4 producing abilities on the CC-chemokine ligand 2-associated herpes simplex virus type 1 infection in human severe combined immunodeficiency (SCID) mouse chimeras

CC-chemokine ligand 2 (CCL2/monocyte chemoattractant protein 1) is known to have an important role on T helper type 2 (Th2) cell generation and described to induce interleukin (IL)-4 production by activated T cells. In the present study, an increase of CCL2 production in cultures of peripheral blood...

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Veröffentlicht in:	Burns 2005-03, Vol.31 (2), p.145-152
Hauptverfasser:	Fujita, Kazuhiko, Sandford, Arthur P., Kobayashi, Makiko, Hanafusa, Toshiaki, Herndon, David N., Suzuki, Fujio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CCL2 Cells, Cultured Chemokine CCL2 - immunology Child Chimera - immunology Coculture Techniques - methods Disease Susceptibility - immunology Female Herpes Simplex - immunology Herpesvirus 1, Human - immunology Humans IL-4 Interleukin-4 - immunology Killer Cells, Natural - immunology Male Mice Mice, Inbred BALB C NKT cells Severe Combined Immunodeficiency - immunology T-Lymphocytes - immunology Th2 cells
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