Safety and immunogenicity of new cell-cultured smallpox vaccine compared with calf-lymph derived vaccine: a blind, single-centre, randomised controlled trial

US government organisations have identified the need for a new smallpox vaccine to replenish limited stocks of the approved, calf-lymph derived vaccine, the manufacture of which is no longer acceptable. We aimed to compare the safety and immunogenicity of the new cell-cultured smallpox vaccine (CCSV...

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Veröffentlicht in:	The Lancet (British edition) 2005-01, Vol.365 (9457), p.398-409
Hauptverfasser:	Greenberg, Richard N, Kennedy, Jeffrey S, Clanton, David J, Plummer, Elizabeth A, Hague, Lynda, Cruz, John, Ennis, Francis A, Blackwelder, William C, Hopkins, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antibodies, Viral - blood Double-Blind Method Humans Lymphocyte Activation Middle Aged Smallpox Vaccine - adverse effects Smallpox Vaccine - immunology T-Lymphocytes - immunology Vaccinia virus - immunology Viral Plaque Assay
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