Mouse Strain–Specific Differences in Vascular Wall Gene Expression and Their Relationship to Vascular Disease

OBJECTIVE—Different strains of inbred mice exhibit different susceptibility to the development of atherosclerosis. The C3H/HeJ and C57Bl/6 mice have been used in several studies aimed at understanding the genetic basis of atherosclerosis. Under controlled environmental conditions, variations in susc...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2005-02, Vol.25 (2), p.302-308
Hauptverfasser:	Tabibiazar, Raymond, Wagner, Roger A, Spin, Joshua M, Ashley, Euan A, Narasimhan, Balasubramanian, Rubin, Edward M, Efron, Bradley, Tsao, Phil S, Tibshirani, Robert, Quertermous, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Aging - metabolism Animals Aorta - metabolism Aorta - pathology Aortitis - genetics Aortitis - metabolism Aortitis - pathology Apolipoproteins E - deficiency Apolipoproteins E - genetics Arteriosclerosis - genetics Arteriosclerosis - metabolism Arteriosclerosis - pathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood vessels and receptors Cardiology. Vascular system Diet, Atherogenic Dietary Fats - pharmacology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Developmental Genetic Predisposition to Disease Inflammation - genetics Medical sciences Mice Mice, Inbred C3H - genetics Mice, Inbred C3H - metabolism Mice, Inbred C57BL - genetics Mice, Inbred C57BL - metabolism Mice, Knockout Oligonucleotide Array Sequence Analysis Reverse Transcriptase Polymerase Chain Reaction Transcription, Genetic Vertebrates: cardiovascular system
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