Bell's Palsy

Bell's Palsy

To the Editor: In his Clinical Practice article on Bell's palsy, Gilden (Sept. 23 issue) 1 recommends treatment of the patient in the vignette with oral prednisone. The Cochrane Collaboration 2 has pointed out that the statement of the American Academy of Neurology — that early treatment with c...

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Veröffentlicht in:The New England journal of medicine 2005-01, Vol.352 (4), p.416-418
Hauptverfasser: Stuart, Michael E, Strite, Sheri A
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal Cortex Hormones - therapeutic use
Bell Palsy - drug therapy
Glucocorticoids - therapeutic use
Humans
Prednisone - therapeutic use
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container_title The New England journal of medicine
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creator Stuart, Michael E
Strite, Sheri A
description To the Editor: In his Clinical Practice article on Bell's palsy, Gilden (Sept. 23 issue) 1 recommends treatment of the patient in the vignette with oral prednisone. The Cochrane Collaboration 2 has pointed out that the statement of the American Academy of Neurology — that early treatment with corticosteroids is “probably effective” 3 — is most likely invalid because their evidence synthesis (i.e., their summary of the best available evidence) included a trial with a high rate of loss to follow-up 4 and a nonrandomized trial 5 — trials that both had serious threats to validity. Without these studies, the pooled results are no longer . . .
doi_str_mv 10.1056/NEJM200501273520420
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subjects Adrenal Cortex Hormones - therapeutic use
Bell Palsy - drug therapy
Glucocorticoids - therapeutic use
Humans
Prednisone - therapeutic use
title Bell's Palsy
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