Reductive Monoalkylation of Aromatic and Aliphatic Nitro Compounds and the Corresponding Amines with Nitriles

A simple, selective, rapid, and efficient procedure for the synthesis of secondary amines from the reductive alkylation of either aliphatic or aromatic nitro compounds and the corresponding amines is reported. Ammonium formate is used as the hydrogen source and Pd/C as the hydrogen transfer catalyst...

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Veröffentlicht in:	Organic letters 2005-02, Vol.7 (3), p.471-474
Hauptverfasser:	Nacario, Ruel, Kotakonda, Shailaja, Fouchard, David M. D., Tillekeratne, L. M. Viranga, Hudson, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Amines - chemical synthesis Formates Hydrogen - chemistry Nitriles - chemical synthesis Nitro Compounds - chemical synthesis Oxidation-Reduction
Online-Zugang:	Volltext
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