Seroprevalence of varicella antibodies in healthcare workers and health sciences students. Reliability of self-reported history of varicella
The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were...
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| Veröffentlicht in: | Vaccine 2005-02, Vol.23 (12), p.1434-1436 |
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| creator | DE JUANES, J. R GIL, A SAN-MARTIN, M GONZALEZ, A ESTEBAN, J GARCIA DE CODES, A |
| description | The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were recruited and a 5 mL blood sample was obtained from all participants. A case report form, including previous self-reported history of varicella, was completed. A total of 91 healthcare workers (mean age, 30.6 years; S.D., 4.0; range, 23-40) and 92 students (mean age, 19.8 years; S.D., 2.5; range, 18-25) were recruited. The prevalence of varicella antibodies was 91.2% in healthcare workers and 92.1% in students. Overall, the sensitivity, specificity, positive and negative predictive values of a self-reported history of varicella were 68.4%, 66.7%, 95.4% and 17.2%, respectively. The preferred approach in these groups at risk of varicella will be to undergo serologic testing before immunization in those with negative or unknown history of varicella. |
| doi_str_mv | 10.1016/j.vaccine.2004.10.003 |
| format | Article |
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Reliability of self-reported history of varicella</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>DE JUANES, J. R ; GIL, A ; SAN-MARTIN, M ; GONZALEZ, A ; ESTEBAN, J ; GARCIA DE CODES, A</creator><creatorcontrib>DE JUANES, J. R ; GIL, A ; SAN-MARTIN, M ; GONZALEZ, A ; ESTEBAN, J ; GARCIA DE CODES, A</creatorcontrib><description>The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were recruited and a 5 mL blood sample was obtained from all participants. A case report form, including previous self-reported history of varicella, was completed. A total of 91 healthcare workers (mean age, 30.6 years; S.D., 4.0; range, 23-40) and 92 students (mean age, 19.8 years; S.D., 2.5; range, 18-25) were recruited. The prevalence of varicella antibodies was 91.2% in healthcare workers and 92.1% in students. Overall, the sensitivity, specificity, positive and negative predictive values of a self-reported history of varicella were 68.4%, 66.7%, 95.4% and 17.2%, respectively. The preferred approach in these groups at risk of varicella will be to undergo serologic testing before immunization in those with negative or unknown history of varicella.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2004.10.003</identifier><identifier>PMID: 15670877</identifier><identifier>CODEN: VACCDE</identifier><language>eng</language><publisher>Oxford: Elsevier</publisher><subject>Adolescent ; Adult ; Age ; Antibodies, Viral - blood ; Applied microbiology ; Biological and medical sciences ; Chickenpox - immunology ; Disease ; Female ; Fundamental and applied biological sciences. Psychology ; Health care ; Health Personnel ; Health sciences ; Herpesvirus 3, Human - immunology ; Hospitals ; Human viral diseases ; Humans ; Immunization ; Industrialized nations ; Infections ; Infectious diseases ; Laboratories ; Male ; Medical personnel ; Medical sciences ; Microbiology ; Population ; Reproducibility of Results ; Seroepidemiologic Studies ; Smallpox ; Spain ; Statistical methods ; Students ; Students, Health Occupations ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><ispartof>Vaccine, 2005-02, Vol.23 (12), p.1434-1436</ispartof><rights>2005 INIST-CNRS</rights><rights>Copyright Elsevier Limited Feb 10, 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16449113$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15670877$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DE JUANES, J. R</creatorcontrib><creatorcontrib>GIL, A</creatorcontrib><creatorcontrib>SAN-MARTIN, M</creatorcontrib><creatorcontrib>GONZALEZ, A</creatorcontrib><creatorcontrib>ESTEBAN, J</creatorcontrib><creatorcontrib>GARCIA DE CODES, A</creatorcontrib><title>Seroprevalence of varicella antibodies in healthcare workers and health sciences students. Reliability of self-reported history of varicella</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were recruited and a 5 mL blood sample was obtained from all participants. A case report form, including previous self-reported history of varicella, was completed. A total of 91 healthcare workers (mean age, 30.6 years; S.D., 4.0; range, 23-40) and 92 students (mean age, 19.8 years; S.D., 2.5; range, 18-25) were recruited. The prevalence of varicella antibodies was 91.2% in healthcare workers and 92.1% in students. Overall, the sensitivity, specificity, positive and negative predictive values of a self-reported history of varicella were 68.4%, 66.7%, 95.4% and 17.2%, respectively. The preferred approach in these groups at risk of varicella will be to undergo serologic testing before immunization in those with negative or unknown history of varicella.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Antibodies, Viral - blood</subject><subject>Applied microbiology</subject><subject>Biological and medical sciences</subject><subject>Chickenpox - immunology</subject><subject>Disease</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Health care</subject><subject>Health Personnel</subject><subject>Health sciences</subject><subject>Herpesvirus 3, Human - immunology</subject><subject>Hospitals</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunization</subject><subject>Industrialized nations</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Laboratories</subject><subject>Male</subject><subject>Medical personnel</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Population</subject><subject>Reproducibility of Results</subject><subject>Seroepidemiologic Studies</subject><subject>Smallpox</subject><subject>Spain</subject><subject>Statistical methods</subject><subject>Students</subject><subject>Students, Health Occupations</subject><subject>Vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0d1qFTEQB_AgFntafQQlIHq3a7L53Esp1QoFoVXwbslmJzTHnM2aZI-cd_Chm-oR0RuvBoZf_jNDEHpOSUsJlW-27d5Y62doO0J47bWEsEdoQ7ViTSeofow2pJO84ZR8OUVnOW8JIYLR_gk6pUIqopXaoB-3kOKSYG8CzBZwdHhvkrcQgsFmLn6Mk4eM_YzvwIRyZ00C_D2mr5ByBdOxjbP1DwEZ57JOMJfc4hsI3ow--HJ4yM0QXJNgialAfeZzienw18Cn6MSZkOHZsZ6jz-8uP11cNdcf33-4eHvdLF2vSyMm7dzUOcUmp7jqmGIj006N0lnVWdpLziXhVJlR0gkIoY6C5rqXhjnJDTtHr3_lLil-WyGXYefzzw1miGsepGJadJT9F1KlJGOCV_jyH7iNa5rrEQMVoieyV1JU9eKo1nEH07AkvzPpMPz-jgpeHYHJ1gSXzGx9_uPqYT2te90DWt2dvw</recordid><startdate>20050210</startdate><enddate>20050210</enddate><creator>DE JUANES, J. 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Reliability of self-reported history of varicella</title><author>DE JUANES, J. R ; GIL, A ; SAN-MARTIN, M ; GONZALEZ, A ; ESTEBAN, J ; GARCIA DE CODES, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p298t-5d8ffd2f73df7472373b38f7b6fc72c1964460417ab61de001f1e84896a3f64a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Antibodies, Viral - blood</topic><topic>Applied microbiology</topic><topic>Biological and medical sciences</topic><topic>Chickenpox - immunology</topic><topic>Disease</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. 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R</au><au>GIL, A</au><au>SAN-MARTIN, M</au><au>GONZALEZ, A</au><au>ESTEBAN, J</au><au>GARCIA DE CODES, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seroprevalence of varicella antibodies in healthcare workers and health sciences students. Reliability of self-reported history of varicella</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2005-02-10</date><risdate>2005</risdate><volume>23</volume><issue>12</issue><spage>1434</spage><epage>1436</epage><pages>1434-1436</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><coden>VACCDE</coden><abstract>The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella history for detecting susceptible subjects. Personnel of a general hospital and students were recruited and a 5 mL blood sample was obtained from all participants. A case report form, including previous self-reported history of varicella, was completed. A total of 91 healthcare workers (mean age, 30.6 years; S.D., 4.0; range, 23-40) and 92 students (mean age, 19.8 years; S.D., 2.5; range, 18-25) were recruited. The prevalence of varicella antibodies was 91.2% in healthcare workers and 92.1% in students. Overall, the sensitivity, specificity, positive and negative predictive values of a self-reported history of varicella were 68.4%, 66.7%, 95.4% and 17.2%, respectively. The preferred approach in these groups at risk of varicella will be to undergo serologic testing before immunization in those with negative or unknown history of varicella.</abstract><cop>Oxford</cop><pub>Elsevier</pub><pmid>15670877</pmid><doi>10.1016/j.vaccine.2004.10.003</doi><tpages>3</tpages></addata></record> |
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| subjects | Adolescent Adult Age Antibodies, Viral - blood Applied microbiology Biological and medical sciences Chickenpox - immunology Disease Female Fundamental and applied biological sciences. Psychology Health care Health Personnel Health sciences Herpesvirus 3, Human - immunology Hospitals Human viral diseases Humans Immunization Industrialized nations Infections Infectious diseases Laboratories Male Medical personnel Medical sciences Microbiology Population Reproducibility of Results Seroepidemiologic Studies Smallpox Spain Statistical methods Students Students, Health Occupations Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye |
| title | Seroprevalence of varicella antibodies in healthcare workers and health sciences students. Reliability of self-reported history of varicella |
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