Haplotype Sharing Analysis Identifies a Retroviral dUTPase as Candidate Susceptibility Gene for Psoriasis

The psoriasis susceptibility locus 1 (PSORS1) mutation is assumed to reside within a region around human leukocyte antigen-C spanning 250 kb, termed risk haplotype (RH) 1/2. By re-analyzing a published data set with a previously developed method, the haplotype sharing statistic, we confirm localizat...

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Veröffentlicht in:	Journal of investigative dermatology 2005-01, Vol.124 (1), p.99-102
Hauptverfasser:	Foerster, John, Nolte, Ilja, Junge, Judith, Bruinenberg, Marcel, Schweiger, Susann, Spaar, Katja, van der Steege, Gerrit, Ehlert, Claudia, Mulder, Marcel, Kalscheuer, Vera, Blumenthal-Barby, Elisa, Winter, Jennifer, Seeman, Petra, Ständer, Markward, Sterry, Wolfram, te Meerman, Gerard
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosomes, Human, Pair 6 Dermatology dUTPase Endogenous Retroviruses - genetics Genetic Predisposition to Disease - genetics haplotype sharing Haplotypes HERV HLA-C Antigens - genetics Human endogenous retrovirus K Humans Medical sciences Polymorphism, Single Nucleotide psoriasis Psoriasis - genetics Psoriasis. Parapsoriasis. Lichen PSORS1 Pyrophosphatases - genetics
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