Defining cancer risk in dermatomyositis. Part I

Summary The idiopathic inflammatory myopathies (IIMs) comprise polymyositis, myositis overlapping with another connective tissue disease, dermatomyositis (DM) and inclusion‐body myositis (IBM). IIMs are characterized by the presence of proximal muscle weakness, increased levels of muscle‐specific en...

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Veröffentlicht in:Clinical and experimental dermatology 2009-06, Vol.34 (4), p.451-455
Hauptverfasser: Madan, V., Chinoy, H., Griffiths, C. E. M., Cooper, R. G.
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container_issue 4
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container_title Clinical and experimental dermatology
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creator Madan, V.
Chinoy, H.
Griffiths, C. E. M.
Cooper, R. G.
description Summary The idiopathic inflammatory myopathies (IIMs) comprise polymyositis, myositis overlapping with another connective tissue disease, dermatomyositis (DM) and inclusion‐body myositis (IBM). IIMs are characterized by the presence of proximal muscle weakness, increased levels of muscle‐specific enzymes, specific electromyographic abnormalities, and the presence of inflammatory cell infiltrates in skeletal muscle. Clinical, serological and histological criteria can be used to define individual IIM subtypes. In the first of this two‐part review series, we examine the evidence for the existence of cancer‐associated myositis (CAM), and in part 2, we discuss recent discoveries that provide insight into identification of patients with DM, who may be most at risk of developing CAM.
doi_str_mv 10.1111/j.1365-2230.2009.03216.x
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subjects Biological and medical sciences
Dermatology
Dermatomyositis - complications
Dermatomyositis - diagnosis
Dermatomyositis - epidemiology
Evidence-Based Medicine
Female
Humans
Male
Medical sciences
Neoplasms - complications
Neoplasms - epidemiology
Polymyositis - complications
Polymyositis - epidemiology
Risk Factors
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
title Defining cancer risk in dermatomyositis. Part I
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