Induction of CRP3/MLP expression during vein arterialization is dependent on stretch rather than shear stress

Aims Cysteine- and glycine-rich protein 3/muscle LIM-domain protein (CRP3/MLP) mediates protein–protein interaction with actin filaments in the heart and is involved in muscle differentiation and vascular remodelling. Here, we assessed the induction of CRP3/MLP expression during arterialization in h...

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Veröffentlicht in:	Cardiovascular research 2009-07, Vol.83 (1), p.140-147
Hauptverfasser:	Campos, Luciene Cristina Gastalho, Miyakawa, Ayumi Aurea, Barauna, Valerio Garrone, Cardoso, Leandro, Borin, Thaiz Ferraz, Dallan, Luis Alberto de Oliveira, Krieger, Jose Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterialized vein graft Biological and medical sciences Biomechanical Phenomena Cardiology. Vascular system Cells, Cultured CRP3/MLP Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Humans LIM Domain Proteins Male Medical sciences Models, Animal Muscle Proteins - genetics Muscle Proteins - metabolism Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Myocardial revascularization Rats Rats, Wistar Reflex, Stretch - physiology Saphenous vein Saphenous Vein - metabolism Shear Strength - physiology Stress, Mechanical Stretch
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